The 29 -year -old nurse has almost disappeared from the advanced liver cancer to the tumor. What did she experience in 576 days?

The Yangtze River Daily Da Wuhan Client August 28 (Reporter Jiang Mengqing) Liang Yi (pseudonym) is a obstetrics and gynecology nurse working in the hospital. At the age of 27, in the third year of promoting the nurse, she was diagnosed with advanced liver cancer. "Live cancer is in the normal cognition, which is about not saved." Liang Yi felt that he was "lucky". From January 29, 2021 to August 28, 2022, 576 days of fighting with cancer, nearly 10 The hepatocytoma of the cm has been reduced to about 3 cm by step. After the right half of the liver surgery was removed in April this year, the tumor was almost disappeared.

"Late liver cancer is not a medicine without medicine, and precise treatment is bringing the gospel to more and more patients." Liang Yi's attending doctor, Professor Zhang Wanguang, Hepat setting the liver surgery center of Tongji Hospital affiliated to Huazhong University of Science and Technology.

Liang Yi rides outdoors and feels spring.

Repeated "letting" hepatitis B evolved towards liver cancer

Liang Yi's family lived in Xiaogan. In junior high school, she was found to carry hepatitis B virus, and the family had a history of hepatitis B, and her grandmother and mother were also carriers of hepatitis B virus.

Hepatitis B is a chronic infectious disease. Its harm is not only to spread, but also continuously invade and damage the liver. Hepatitis cirrhosis and even liver cancer may occur.

"At that time, the doctor on the hometown said that he didn't need to take medicine and reviewed it regularly, but we had never cared about it. Later, we were busy at work and ignored this."

After graduating from the nursing major in 2016, he first worked as a nurse in a local hospital in Xiaogan. The obstetrics and gynecology shaft rotation is the normal work. "Thinking about being young, we must work hard, so I will put pressure on myself in terms of work intensity."

In 2018, Liang Yijin was promoted to the head nurse, and the "tumor" of liver cancer in the same year has begun to see in the body. In the annual medical examination of the employee, her body was different. The doctor said that there was something on the gallbladder, and it was best to check what it was. Liang Yi, who was born in care, heard that it was gallbladder, and felt that it should be fine and did not pay attention.

Near the Spring Festival found that the liver has a "egg" big malignant tumor

The hidden dangers of continuous high -intensity work broke out two years later. In December 2020, Liang Yi often felt a little uncomfortable in the waist, and urinating would feel a little fever. At first, I thought it was a small problem with the kidney. The symptoms have not eased. Doctors recommend checking in the liver.

On the day of the diagnosis, Liang Yi went to the hospital alone to get a diagnosis report. The doctor told her that the liver had an egg -sized tumor, 91 mm × 77 mm, close to 10 cm, and the liver tumor invaded the door veins and the internal liver metastasis. It was late. Examination signs that it may grow in the body in 2018. Based on the current diagnosis, patients have no indication of surgery.

"At that moment, I was very panicked and I was very afraid. I couldn't accept why I was myself? I don't know how to tell their parents when I returned to my hometown in the New Year." Liang Yi remembers that day that day was January 29, 2021, near the Spring Festival, walking out of the hospital, the streets and alleys successively successively The people who hung the lantern, hurriedly played the New Year's goods, and the festive music of the shop rendered the atmosphere of the New Year. At that time, Liang Yi suddenly felt that he was the "outsider" of this lively world.

She walked sluggishly on the road, as if she had lost her soul, and she didn't know how long she had gone until she received a call from her brother that she couldn't help crying.

"Do surgery or liver transplantation, which method can be treated for you, I will find a way, as long as it can be cured, it can be cured." The brother said calmly and firmly, and encouraged Liang Yi to actively treat it.

Each chemotherapy has a feeling of "escape from death"

After that, Liang Yi stopped his work and moved back to his hometown. Xiaogan and Wuhan were treated at two o'clock. However, the effect of iodine oil C-TACE intervention therapy for the first time on February 3, 2021 is not satisfactory. The key indicator nail protein (APF) value of the key indicator of liver cancer tumors will not increase and increase, breaking the 12000ug/L.

Liang Yi knew what this data meant, but after the treatment returned home, she always behaved calmly. She did not dare to show her fear in front of her parents.

My brother -in -law asked the little sister's condition, and was recommended by his friends to find Professor Zhang Wanguang, Wuhan Tongji Hospital.

"Precision treatment -oriented treatment of genetic testing, through accurately identifying cancer cells, evaluating the patient's tumor biological characteristics, and looking for targeted and effective targeting drugs, combined with immunotherapy, some patients have the opportunity to extend, even even. There is a possibility of healing. "Professor Zhang Wanguang introduced.

Professor Zhang Wanguang interpreted Liang Yi's inspection report on WeChat and encouraged her to continue to treat.

Professor Zhang's treatment ideas, like a light shining into the bottom of the valley, gave Liang Yi a great confidence in the desperate despair.

"I am still young, I want to grab it in one line, and I will try it."

Fortunately, it was found that Liang Yi's FGF19 gene expanded through blood testing through blood, and the immune score reached 18 points. A targeted combined immunotherapy was targeted. Through preoperative adjuvant treatment Relief is reduced, which can reduce the scope of the liver and improve the effect of surgical.

From March 2021 to early April 2022, Liang Yi came to Tongji Hospital in Wuhan every 21 days to review it from Xiaogan, received a medicine microsphere D-TACE intervention therapy, fourth hepatic arterial infusion chemotherapy (HIAC), multiple Immunotherapy for this course of treatment ...

Injecting chemotherapy is a pioneering mouth of the size of the needle eye from the root of the thigh, and a catheter is directly connected to the arterial blood vessels of the liver cancer cells in the liver to accurately administer it. Liang Yi responded to a great response to chemotherapy drugs. Basically, as long as chemotherapy was on, she would always vomit, and once the medicine was hit, she could not stop in the middle. The first chemotherapy would last for nearly 2 days. Liang Yi said, "Every time she goes to the hospital, she is afraid of the results, but every time I go to the treatment, I seem to have more hope again, and I feel like an escape in death."

After surgery for assistance, Liang Yi tumor indicator was normal and expressed his gratitude to Professor Zhang Wanguang.

After 14 months of surgery, Liang Yi's tumor was reduced to 30x42 mm, about 3 cm. Magnetic resonance evaluation is completely alleviated by the tumor. Although the magnetic resonance did not show obvious activity, CTDNA examination was positive in the two blood, Professor Zhang Wanguang suggested that surgical resection.

On April 8, 2022, under Professor Chen Xiaoping, an academician of the Chinese Academy of Sciences, Liang Yi successfully underwent the right half hepatic tumor resection surgery. The cut tumor pathological examination had no tumor cells. More importantly, the CTDNA test in her blood is continuous negative.

Precision Medical Patients Patient Survival Patient Survival Patients

Looking back at the 576 -day treatment process, Liang Yi felt that he was a beneficiary of medical progress. Now she jumps at home every day to exercise, adjust her lifestyle, and enhance physical immunity. For another half a year, she can consider re -work in April next year to return to her normal life.

Liang Yi and his family played together to relax.

According to Professor Zhang Wanguang, according to the statistical analysis of Academician Chen Xiaoping of Tongji Hospital five years ago, 40,000 patients with liver cancer patients in the country had less than 15%after liver cancer surgery. However, the 5 -year survival rate of experienced medical centers can be as high as 60%.

"Precision treatment is rewriting the definition of advanced liver cancer. Previously, the tumor was considered to be particularly large, and the liver metastasis could not be cured. The current definition should be that the liver function cannot tolerate drug treatment, that is, liver cancer is called advanced liver cancer. "

Professor Zhang Wanguang further explained that as early as the beginning of the 21st century, Professor Qiu Fazu proposed the "one -handed surgery knife and geneticism in one hand" in the book "Basic Surgery". During the period of accurate treatment, genetic testing is the core information of solving life, the comprehensive improvement of targeted drugs, immunotherapy, and precision diagnosis and treatment technologies. A considerable number of patients can get longer survival and even heal.

“医学既往的目标为偶尔是治愈，常常去帮助，总是去安慰。通过精准治疗能够有希望改写为一直是帮助，常常是治愈。在这个征程中，医生需要不断学习创新，结合基因检测和Precision treatment concept, multi -disciplinary cooperation model, and the optimal treatment plan for patients to increase the prognosis and quality of life. "Professor Zhang Wanguang said.

[Edit: Yu Lina]

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