Tribute to Chinese Physician's Day

Physician News: Qin Miao

Medicine is more learning, people, and the ultimate interests of people! Doctors who shoulder this social cause are naturally needed, attention, and measured at all times, and the "deep love" of the outside world can easily make this group may be deified or misunderstood. When returning to the original intention, what is the doctor? From the perspective of Li Jian, deputy director of the Department of Gastrointestinal Department of Peking University Cancer Hospital, this is an ordinary occupation that is accidentally hit, a tireless exploration to seek new, and also the responsibility of Taishan and Jingyou's life.

Fate: Parent's life, the path of "hot" for "hot"

Li Jian, as the leader of gastrointestinal gastrointestinal tumor diagnosis and treatment, has many titles such as the chairman of the China Clinical Oncology Society of the Gastrointestinal Gastrointestinal Society and the Standing Committee of the Clinical Research Committee of the China Clinical Oncology Society. He published more than 40 SCI and core journal papers, and won the Huaxia Medical Science and Technology Award twice, and was rated as the "National Medicine of the State". Behind these honors and halo, Li Jian has been like most ordinary people, and the "medical road" choice is deeply influenced by parents.

The relationship between Li Jian and medicine originated from the expectations of his parents to work in stable work. The doctor is undoubtedly the representative of the "iron rice bowl" in the eyes of his parents. "I was interested in the economy and finance at that time, and I would like to be a professional journalist in the future, so my personal willingness was the Broadcasting Institute." The glass syringes and steel needles used by children and doctors are impressed with "horrible", so I never thought of studying medicine. "But with the advice of his parents, he finally chose to cater to his parents' expectations and stepped into the endless medical path.

The major that was slightly helplessly chosen, Li Jian found fun in the vast ocean of knowledge, obsessed with the wonder of life science. "I feel very interesting when I study. When I am a senior clinical trainee, I can integrate the knowledge of college learning into the work, and I feel more interesting." Li Jian said, but the interest is not the whole of clinical work. Really understand that the doctor's work is ordinary and extraordinary. Daily handling, checking houses, and opening doctors on the surface are the constitutional life similar to ordinary white -collar workers. But behind it is about life and health, and no rigorous and stress on the slightest. I don't know the whole picture, it is difficult to get the accurate portrait of the doctor, so they need more respect and tolerance of the outside world.

Li Jian became a tumor specialist, and there were some accidental. Just like the "big factory" complex of ordinary people's job hunting, when Li Jian University graduated from Li Jian University in 1998, based on the trust of the "university affiliated hospital", he went to the unknown Northern Medical Affiliated Oncology Hospital at that time. At that time, the scientific development of oncology, especially the internal science of tumors, was immature. Due to too few treatment methods, there were no special effects drugs. Compared with the surgical and Cardiology, these are quite unpopular majors. However, because doctors like Li Jian have devoted themselves to it, the rapid development of the oncology discipline has developed rapidly in the future, and it has almost become the fastest discipline in the field of internal medicine. Variety.

Recalling the original choice, Li Jian felt very lucky and accidentally hit the oncology discipline, but caught up with the opportunity to develop and was influenced by the North Medical System, achieving the mutual achievements of individuals and the industry.

Depth of love: stay with the patient, let the tumor completely become a dream of slow disease diagnosis and treatment

Tumor diagnosis and treatment have become hot keywords in the current medical community, but in the early stages of development, there were very few drugs for detecting and treatment methods. ——Pymatic patients are mostly advanced, and clinical cure is difficult, and many doctors have retreated on tumor majors. "Especially when you encounter young patients who are very late, the doctor is helpless, watching his life disappear, and his heart is very torment." Li Jian said.

Before the 1990s, it belonged to the era of tumor chemotherapy. The treatment methods were limited and chemotherapy drugs had a large side reaction. It was the most difficult era. Until 2000, targeted drugs pushed tumor therapy into the era of targeted therapy for "precision crackdown on biological missiles". The drugs were no longer attacking human cells like early chemotherapy, and the target accuracy and efficacy were improved. From now on, the countdown to the countdown is the third revolutionary era of tumor diagnosis -immunotherapy era. At this time, no longer relies on drugs to kill the tumor, but to mobilize the human body's own immune cells to kill the tumor , Basically reverse the development of tumors. At this time, you can talk about the "thorough healing" of the tumor.

In the past three eras, the five -year cure rate of tumor patients has increased significantly or even partially reached a thorough cure. The former "terminal illness" has now become "chronic diseases" that can be controlled and controllable. Li Jian pointed out: "We are getting closer and closer to turning tumors into a complete stage of chronic diseases!" And achieved such great results. He believes that it is inseparable from the progress of scientific research and the research and development of new drugs. But the deeper factors come from the patient, the doctor to get feedback, accumulation into experience, and then transform from the patient.

Li Jian said that clinically, old doctors are usually considered more experienced and trusted. But every doctor has been young and grows from medical "little white" to experienced experts. The growth on the way is inseparable from the patient's company and long -term consistent. For more than 30 years of tumor diagnosis and treatment, Li Jian's most touched him was the old patient who gave him support and stayed for more than ten years when he was young.

"When I was the doctor of the doctor, I started to do gastric and intestinal tumor diagnosis and treatment, and most doctors would be strange to this disease. Therefore, when I was out of the clinic, the new drug indications and patient disposal were right. It needs feedback to patients. "Li Jian told reporters that in that circumstances, facing strange diseases, young doctors, the trust, support, and information feedback given by patients are the key to support him to accumulate more in this field Essence Li Jian emphasized that doctors and patients are a comrade -in -arms of trenches. The common enemy is a disease. In the face of difficulties, the tumor diagnosis and treatment will make the tumor diagnosis and treatment from the initial injury to 800 self -damaging, and enter the entered into the first one thousand. The current era of individualized and precise diagnosis and treatment also gives him personally have a deeper insight and emotion on medicine. Inheritance: Give young people, redefine a good doctor in the new era

The Department of Gastrointestinal Department of Peking University Cancer Hospital is the earliest domestic digestive tract malignant tumor diagnosis and treatment center. The professional strength is far ahead of the country. The overall number of clinical trials of the department leads the number of clinical trials in the country is also among the best in the country. Li Jian believes that the core competitiveness is "someone and do something"! In terms of gastric cancer diagnosis and treatment, there is a historical sedimentation of the older generation of "leaders" -Directors Jin Yilin, the founder of the department, opened the territory for advanced gastric cancer; the pioneering and aggressive forgiveness of the backbone -Professor Shen Lin, director of the current department, led the team to strengthen the team to strengthen the team to strengthen Research on transformation, quickly promote the diagnosis and treatment of precision gastric cancer; there are also young doctors who are tireless and the hospital is willing to give young doctors a chance to promote their rapid promotion of growth.

Li Jian said that the atmosphere of their entire team's development was particularly good, and they worked together to achieve the vigorous state of the discipline, making the department steadily among the first square of gastrointestinal tumors in China. At the same time, the team adheres to the concept of always innovation and continues to break through in the field of clinical research:

First, establish the earliest domestic gastrointestinal tumor gene testing platform. Carrying out intestinal tumors, colorectal cancer KRAS gene testing, etc., are all early detection of tumor -specific genetic tests that are unwilling to do and unconventional in other hospital digestive tumors.

Secondly, the establishment of a wealth of animal models, especially human -oriented mice models. The use of several generations of reproduction and tumor gene models that are very similar to people for drug efficacy monitoring and new drug research and development have greatly promoted the development of diagnosis and treatment safety and innovative drugs.

Third, study the value of peripheral blood in the efficacy of tumor, and establish a multi -dimensional biological sample detection and functional verification platform.

Fourth, carry out the application research of CAR-T immunotherapy in digestive tumors. CAR-T has a good effect on treating blood disease, but it is difficult to treat solid tumors, so researchers at home and abroad are unwilling to touch this subject. However, Peking University Cancer Hospital has made a very good progress in the Department of Gastrointestinal Incurities and made very good progress.

"CAR-T treatment of advanced gastric cancer and pancreatic cancer is very good, which is far better than chemotherapy and targeted treatment. Before the emergence of immunotherapy, many advanced gastric cancer patients rely on long-term and continuous medication to inhibit tumor growth and apply CAR- After T treatment, the medication can be maintained for a year or even a long time. The quality of the patient's life is high and can return to the family and society completely. This is the traditional treatment method. The international authoritative academic journal "Nature Medicine" was published and published on the cover of the journal. Li Jian was the first author.

Li Jian emphasized that the current tumor diagnosis and treatment concept and means have undergone tremendous changes compared with his just getting started, so they need to keep up with the times and develop innovation. This requires seizing opportunities to seek development, and to create opportunities to promote development. "Especially in China, such as gastric cancer, esophageal cancer, high -incidence and special diseases, waiting for the scientific results of other people (Western countries) to wait, we can only solve it by ourselves."

In the end, Li Jian expressed his entrustment to the young doctor. He said: "Oncology is a specialty of multi -disciplinary integration. Oncologists must also be a" multi -faceted "to have multiple skills, such as: developing immunotherapy, which needs to be half immunohistic experts; precise targeted treatment, You have to understand the target detection, related signal channel problems, etc. It is difficult to be a good doctor in the future, and it is more difficult for good oncologists to be! Previous doctors only need to do 'Nothing Wrong', which is easier to copy guidelines. However, in the era of precision medicine, a real good doctor must be 'thousands of people and thousands of squares', and individualized diagnosis and treatment plan is the future direction of tumor diagnosis and treatment! "Therefore, he suggested that young tumor doctors first play the knowledge foundation of Grand Sciences, and And break the limitation of college and strengthen the integration of multidisciplinary knowledge. It is best to plan in advance during college to maximize the interests of patients' interests.

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