What is DNA methylation?What does it have to do with aging?
Author:China Food Industry Magazine Time:2022.08.15
For a long time, people think that aging is a kind of loss, irresponsible, irreversible, just like the mobile phone has been used for a long time, and it will inevitably occur. When the problem accumulates to a certain degree, it can only be abandoned.
But in fact, in April 2021, the internationally renowned journal "AGING" released a random control clinical study: in just 8 weeks, only by changing the diet and lifestyle, the test group realized "anti -age growth", physiological physiological The age is more than 3 years younger than the control group.
This study first confirmed that specific diet and lifestyle intervention can change the DNA methylation epigenetic process, reverse the apparent genetic aging of healthy adult men, and improve human health.
At the same time, recently, Chinese scientific researchers have also studied that DNA methylation can regulate gene expression by integrating environmental signals and play a key role in aging.
Many people may ask, what is DNA methylation? What does it have to do with aging?
DNA methylation level predicting physiological age is one of the internationally recognized methods of the most authoritative evaluation of aging. DNA methylation is actually the process of adding methyl group to DNA's cytopine. It is one of the important mechanisms of the table -viewing genetics, which can activate or silent certain genes. A large number of studies have shown that DNA methylation can cause changes in chromatin structure, DNA structure, DNA stability, and DNA interaction with protein, thereby regulating gene expression.
Many species including humans will occur with DNA methylation with age. Modern people's pressure, staying up late, drinking for alcohol, coupled with diseases, aging and other factors, can leave marks on DNA through apparent genetic methods such as DNA methylation. Simply put, aging is often accompanied by decreased methylation activity. If the degree of DNA methylation, the smaller, the smaller the calculated physiological age, and the smaller the degree of physical aging.
So we can start with DNA methylation to delay the aging process. In addition to a good diet and lifestyle, some proprietary Chinese medicines with unique treatment advantages will also have a positive impact on our DNA methylation age.
Chinese scientists have made significant progress in DNA methylation. The latest research on the "Theory Guidance of Eight Soning Kidney Anti -Aging Research Projects" carried out by the National Key Laboratory of the National Key Laboratory of Traditional Chinese Medicine State Medicine State Medicine Studies shows that in the 2 -month experiment, 60 weeks of aging mice (equivalent to people are equivalent to people The 50 -year -old was given to the eight sons, and the aging mice were reversed to 40 weeks after 2 months (equivalent to the age of a person). Therefore, the eight -son tonic became the first compound Chinese medicine that was confirmed to improve the age of methylation.
With the increase of age, the level of armor -based opticalization of the human body will change, which will affect the expression of the genes. This is why it is also forty or fifty years old. Some people are still upright, delicate, and full of youthfulness; while some people are under the pressure of work and life, they are white, wrinkled with wrinkles, waist and back, back and back. Camel is a teenage older than his peers, that is, the physiological age is greater than the actual age. Studies of scientists have found that eight -son tonic can not only improve the level of methylation, delay aging, and treat a series of diseases in the process of aging, such as atherosclerosis, osteoporosis, and degenerative lesions of the central nervous system. Multi -target intervention adjustment effect.
It can be seen that as long as we understand the process of aging and want to reverse aging, it is not difficult. These studies mentioned above not only inspired scientists to continue to explore DNA methylation and aging connection, but also gave us ordinary people confidence.
Through the synergy of diet, exercise, sleep, and drug intervention, it plays a significant role in slowing DNA methylation and effectively reduced the physiological age. Therefore, we can also learn from our daily life to delay aging and promote health to a greater extent.
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