Autumn and winter are coming.

The 21st Century Business Herald reporter Wei Xiao Shenzhen reported that after the beginning of the autumn, the weather began to cool from heat. The autumn and winter seasons are also the high incidence of traditional flu. At present, the world is still in the stage of new crown pneumonia. Therefore, experts have studied and judged that the risk of influenza and new crown pneumonia may occur in the autumn and winter of this year or the spring of the next year.

On August 10, at a press conference held by the joint control mechanism of the State Council, Dong Xiaoping, chief expert of the China Centers for Disease Control and Prevention Center, pointed out in a reporter from the 21st Century Business Herald that from 2020 to 2021 Public sanitation measures, influenza shows a low level of popularity, which leads to a relatively low proportion of crowds that lead to natural infections. In addition, the level of vaccination in my country's influenza vaccination is low, so the immunity of influenza virus pre -deposit in the crowd has decreased. Dong Xiaoping pointed out that in the summer of 2022, the popular peak of A (H3N2) subtype influenza virus had appeared in the south, and the possibility of influenza epidemic risk in the autumn and winter of 2022 was high.

Recently, Lu Hongzhou, the dean of Shenzhen Third People's Hospital, published a paper and pointed out that in the era of COVID-19, flu, but the influenza seemed to have been "ignored", but in fact, the flu has never disappeared.

The influenza under the new crown is "ignored"

Recently, the Shenzhen National Infectious Disease Clinical Medicine Research Center/Shenzhen Third People's Hospital (Second Affiliated Hospital of Southern University of Science and Technology) published a paper "COVID-19 Popularity Challenges: Fluid of the Popular Age" in "Bioscience Trends", Lu Hongzhou, Dean of Shenzhen Third Hospital, and Zhu Mingruo, a professor at the environment and population health center of the Medical College of the University of Greez University, Australia, as the author of the joint communication.

Since its popularity in 2019, COVID-19 has been a hot topic in the world. Due to the generally adopted public health measures to prevent COVID-19 popular, the incidence of influenza has also decreased at the same time. In the era of COVID-19, flu having seemed to be "ignored", but in fact, flu never disappeared.

Influenza is the most challenge of the world's most public guards. "Big Influenza Popularity" is generally used to describe the influenza in 1918, that is, the fatal global H1N1 influenza virus is popular. The disease was infected about 500 million people at the time and caused about 2470-39.3 million people to die.

Lu Hongzhou's team pointed out that although public health measures to prevent COVID-19 also reduce the risk of people's influenza, it also reduces the adaptive immunity of the population to influenza. Although the current influenza is not focusing on the focus, adaptive immunity in the group may cause future influenza epidemic; in addition, the combined infection of COVID-19 and influenza may also be the problem of spine. Therefore, governments should take measures to prepare for the popularity of influenza in the future.

Dong Xiaoping also pointed out that from 2020 to 2021, due to my country's relatively strict public health measures, influenza showed a low level of popularity. The long -term low level of popularity has led to a relatively low proportion of crowds that are infected. In addition, the level of vaccination in my country's influenza vaccine is low, so the immunity of influenza virus predicts in the crowd has decreased.

According to the World Health Organization (WHO) estimates, there are about 1 billion new influenza cases worldwide in the world, including 3 million-5 million cases of severe cases and 29-65 million death cases. According to data from the global influenza monitoring and response system, WHO shows that from May 30 to June 12, 2022, 107 countries reported 161,959 influenza virus samples, of which 97.5%were type A influenza and 2.5%were type B influenza.

Although the total global incidence in the second wave of influenza in 2022 is low, data from China and Australia show that fluctuations have increased significantly. According to data from the National Fluent Center, Guangdong Province recently reported 126,857 new cases, which was 10.38 times last year.

The situation in Australia is also worrying. The statutory infectious disease monitoring system in Australia reported 147155 cases during this wave of influenza epidemic, of which 55,101 cases were reported from June 6 to 19, 2022, and 6.1%of patients with severe influenza were reported. Usually 300 times. The "dual popularity" of COVID-19 and flu is a difficult issue facing the Australian government.

The Lu Hongzhou team pointed out that the situation in China and Australia showed that although this is the era of COVID-19, the problem of influenza is far from being resolved.

Be wary of the new crown and influenza infection

In the context of this "dual popularity", there is still a key issue, namely the combined infection of COVID-19 and flu.

Lu Hongzhou's team pointed out that recent large-scale clinical studies have reported the combination of COVID-19 and influenza infection in the COVID-19 and British COVID-19 in the United States, the United States, Australia, Chile, Nanda, Nanga, Nanga, and Britain.

For example, KAWAI et al. Plugs in the diagnosis of ⽤ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ ⽅ 例 193 COVID-19 patients were retrospectively studied, and no cases of infection of COVID-19 patients combined with influenza. Therefore, it believes that the merger infection of COVID-19 and flu in Japan in the winter of 2020, but it points out that the dual infection of the new crown and flu in the secondary influenza season; Ozaras et al. Six of the patients were infected with influenza (0.54%) at the same time, and all patients with dual infections were mild to moderate infection; Swets et al., While Swets and others tested 6,965 new patients in the UK, and found 227 patients with influenza (3.26%3.26% To. It is worth noting that the Lu Hongzhou team pointed out that although these studies have agreed that there are fewer cases of combined infection in the new crown and flu, we still need to pay close attention to this situation, because we still know very little about the clinical prognosis of double infection patients.

In addition, Swets and others have found that double infections are significantly related to patient mortality. In addition, at the same time, the infection of new coronary viruses and respiratory viruses greatly increase the probability of patients with mechanical ventilation. The study predicts that the combined infection can lead to a worse prognosis of patients, but the real situation needs further research and support.

The Lu Hongzhou team pointed out that the interaction between COVID-19 and flu is very complicated. The mechanism has not yet fully understood. The following issues need to be paid attention to. First of all, as a respiratory virus, the two viruses have similar communication characteristics and common clinical manifestations. Therefore, measures to prevent COVID-19 can also effectively prevent influenza. The incidence of influenza is related to public health measures (such as wearing masks, blocking cities, and maintaining social distance) adopted for COVID-19.

But on the other hand, priority considering COVID-19 and ignoring influenza may lead to decline in adaptive immunity to influenza in general populations, and increase the risk of influenza infection, especially among specific elderly people and people with certain potential diseases. Essence

In addition, studies have shown that infection COVID-19 often involves common infections with other respiratory viruses. However, it is extremely difficult to distinguish COVID-19 according to the symptoms in the early stage, and more effective identification diagnostic tools are needed. Except for PCR testing, the results of chest radiology can help to screen patients with COVID-19 and influenza infection.

Lu Hongzhou's team pointed out that in general, the combined infection of COVID-19 and flu in the future may be a tricky issue. Public health institutions around the world should be aware of this and make preparations in advance, especially the upcoming influenza season. In addition, more effective vaccine and antiviral drugs should be developed, as well as continuing to update and strengthen popular science propaganda on preventing COVID-19 and influenza.

In response to the risk of "double pop", how can my country deal with it? Dong Xiaoping pointed out to the 21st Century Business Herald that the first is to monitor the level and characteristics of the fluidth and new crown pneumonia activities for a long time. Through the dynamic risk assessment of the whistle hospital, the monitoring outlets, and the laboratory, the early warning information is released. The second is to investigate and check the patients with hot kidneys, and timely identify and diagnose influenza and new crown pneumonia. Third, once the epidemic occurs, the local area will adopt necessary public health measures based on the risk assessment of the epidemic. While preventing and controlling the new crown pneumonia, it can also effectively reduce the spread of flu. The fourth is to actively promote the vaccination work of influenza vaccine. In 2022, the influenza vaccine approval time was issued earlier. It is recommended that all localities prepare for flu vaccination in time.

"Autumn and winter is coming. Here we call on the public to prevent and control respiratory infectious diseases. Before the influenza season comes, influenza vaccination should be performed early, especially the elderly and medical workers. Symptoms, you should seek medical treatment in time, and usually do personal protection, including hard -handed hands, wearing masks, constant ventilation, less gathering, etc. "Dong Xiaoping said.

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