Sohu Pharmaceutical | Scientists irrigate artificial blood for short -term "death" pigs and successfully "resurrected"

Author:Sohu Health Time:2022.08.11

Produced | Sohu Health

Author | Zhou Yichuan

Edit | Yuan Yue

The cardiac arrest is required to "four minutes of platinum". After the organ stops, the organ will quickly cause irreversible damage, and ischemia for ten minutes can cause death. However, the future emergency time may be longer. On August 3, Yale Medical College introduced that scientists irrigated artificial blood for short -term ischemic pigs, successfully reversed damage, and "resurrected" organs.

Experts introduced that after the heart stopped, the organs will be ischemia and hypoxia, the accumulation of carbon dioxide occurs, the harmful substances are released in blood, and the cells are quickly damaged and died. Experts have designed a kind of oxygen content, normally acidity, and artificial blood containing various types of biochemical substances, and anticoagulants and anti -inflammatory drugs. The ORGAN EX system is used to supply blood for ischemia.

The experiment was used to stop the heartbeat with electric shock. After 1 hour of cell function recovery treatment, connected ORGAN EX and in vitro cardiopulmonary system. After 6 hours of treatment, it was found that artificial blood perfusion pigs have better blood supply to pigs in the cardiopulmonary system and have less cell mortality, while many smaller blood vessels have collapsed.

There are three application potential for this system:

1. Extend the life of the transplantation. The cells gradually died after the organs were separated. This system can maintain cell life, extend the transfer time, and increase the success rate of transplantation.

2. Treatment of stroke and myocardial infarction. Artificial blood can treat cell damage caused by ischemia, hoping to restore organ function.

3. Reverse death. Is the heart stopped due to drowning and other heart stopping, can artificial blood reverse death? The future is full of possibilities.

There is also a terrible problem. If the irrigation only restores half of the organ function, it may make patients more painful and need more tests to eliminate risks.

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