Xinglin Baojian | Talk about whether Chinese medicine will cause liver injury

Author:Guangdong Provincial Hospital Time:2022.08.10

Medical Guidance:

Lin Yi, the fourth Chinese medicine master, the first "National Famous Traditional Chinese Medicine", a master of Chinese medicine, enjoys special allowance experts from the State Council.

Disposal time:

Monday morning: Twenty -Floor Breast Diagnosis and Treatment Center, 10th Floor, Daode Road General Hospital of Guangdong Provincial Hospital of Traditional Chinese Medicine

Tuesday morning: The Department of Breast Department, 5th Floor, Outpatient Clinic of the University of the University of Traditional Chinese Medicine

Wednesday, Friday, Saturday morning: The Department of Breast Department of the 2nd Floor, Outpatient Clinic of Ersha Island Hospital of Guangdong Provincial Hospital of Traditional Chinese Medicine

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[Xinglin Baojian] Breast health is not only beauty, but also love, but also the source of life. The breasts are great and fragile. Caring for breasts, caring for women is not only the responsibility of medical workers, but also the responsibility of the whole society. Xuanqi Huang's Way, passing the meaning of Xinglin, from the case of famousians, specialty methods to health care, and science of dairy disease, and talk to you.

"Can Chinese medicine be eaten? Will it hurt the liver?" "I heard that you ca n’t take Chinese medicine at the same time when taking western medicine, which will affect the liver function." In the outpatient clinic, patients often asked Professor Lin's questions. The incident of "Chinese medicine hurts the liver" seems to be widely spread and deeply rooted in people's hearts. But is the actual situation really?

Chinese herbal medicine is not the main cause of drug -induced liver injury in mainland China

Recently, the first pharmaceutical liver injury related adverse reports were released in mainland China. The report showed that in the report of drug -related hepatitis related adverse reactions in 2012-2016, Chinese herbal drugs accounted for 4.5% 0.8%, other proportion of 0.2%. The top 50 suspected liver injury drugs in the report are chemical drugs and biopharmaceuticals. Among them, antibiotics (mainly anti -tuberculosis drugs), cardiovascular drugs, and antitumor drugs rank among the top three.

This article shows that the main cause of clinical drugs in my country is chemicals. Chinese herbal medicine is not the main cause of drug liver injury.

Which drugs can cause medicinal liver injury?

目前，已知有1100多种上市药物具有潜在肝毒性，常见的包括非甾体类抗炎药、抗感染药物（含抗结核药物）、抗肿瘤药物、中枢神经系统用药、心血管系统用药、 Metabolic diseases, hormone drugs, etc. Of course, this also includes some Chinese herbal medicines and proprietary Chinese medicine preparations.

Commonly used single -flavored traditional Chinese medicines that may cause liver injury are: yellow medicine, Raygi vine, Cangei, ephedra, Ho Shouwu, Kawabuzi, ostelastial, Jinbu, orpi leaves, 槲 parasites, etc. There are strong bone arthritis, silver pills, ringworm, Xiao Chaihu soup, compound Qing Dai pills, Dahuoluo pills, Yiyu Ning, brain decay, eliminating Shi Dan, compound cough, stasis pills, thirst pills, thirst pill, Gastrodia pills, Shouwu tablets, cough asthma, beef and poison tablets, etc.

Should we "talk about poison and color change"?

Clinically, patients and even some doctors often have "poisonous changes" when they encounter Chinese herbal medicines. They should not be taken. In fact, it is not advisable to put aside the "poisonous color change" behavior of drugs and doses.

First of all, we must make it clear that in addition to the more than 100 Chinese herbal medicines and its related preparations that may cause liver injury under certain circumstances, most of them only need to be used reasonably and correctly, which will not cause liver injury. Therefore, it is not desirable to generalize the perception of "toxic Chinese medicine" that may cause liver injury in the traditional Chinese medicine that may cause liver injury in the unsatisfactory drug composition.

Secondly, it is irrational for any perception of dosage toxicity. For example, for Ho Shouwu, which may cause liver injury, the safety dose of drugs has long been clearly stipulated. The 2020 version of "Chinese Pharmacopoeia" clearly stipulates that the amount of Ho Shouwu is: 3-6g; the amount of Ukraine is: 6-12G. In addition, the State Food and Drug Administration issued the "Notice on Strengthening the Relevant Regulations on Strengthening He Shouwu Health Food Supervision" in 2014, which clearly stipulates that the amount of Shouwu Shouwu in health foods must not exceed 1.5g in health foods; Do not exceed 3.0g. In other words, it is safe to use Ho Shouwu reasonably.

Related clinical studies also pointed out that in all the adverse reactions caused by He Shouwu, more than half of the adverse reactions caused by the patient's own purchase of drugs; nearly 30 % of adverse reactions due to ultra -dose medication. This reminds us that the use of drugs on its own under the guidance of a doctor is more serious and dangerous than the harm that can be caused by the drug itself!

Toxic is also effective, how to choose?

Is it impossible to use "toxic" Chinese medicine? In fact, a large number of clinical studies have confirmed that if some toxic Chinese medicine is used properly, its curative effect is very significant. For example, spots are toxic ingredients contained in spots, but it can inhibit the synthesis of nucleic acids and protein of cancer cells, affecting the cancer nucleic acid metabolism and killing cancer cells. Therefore, it is not advisable to "refuse the door" just because of its toxic. The component of the component of the component of the component of the component of the component has long been listed as a Chineseopathic medicine. Its efficacy is to break blood and dispel blood stasis, attack toxic and eclipse, and clinically can be used for primary liver cancer, lung cancer, rectal cancer, malignant lymphoma, and gynecological malignant tumors. Essence It can be seen that "poison" is used well and benefits greater benefits.

How to do to avoid medicinal liver injury?

How to use Chinese medicine and related preparations that may cause liver injury? Professor Lin Yi brought a few warm reminders to the majority of patients.

① Please follow the doctor's advice

As mentioned earlier, the source of the case of most Chinese herbal medicine liver injury clinically caused by blind medication. For example, some folk "prescriptions" and "creamy prescriptions", such as Chinese medicine or prescriptions that have not been recognized by doctors and the prescriptions reviewed by the pharmacist may be the main culprit that leads to liver injury of traditional Chinese medicine. Some patients also increased their dosage or extended medication time, which led to liver injury. Therefore, it is recommended that you must follow the doctor's advice and do not trust the recipes of the recipe.

② Do not make up blindly

In the clinic, Professor Lin Yi often encountered the "tonic army", holding a long list, and asked if he could take it one by one. Whenever at this time, Professor Lin Yi reminds patients: It is better not to supplement the wrong and tonic. In fact, as long as we arrange dietary dietary daily, we can supplement most of the nutrients needed by the human body, without the need to be blind, extra, and a lot of tonic. For the "tonic" popular on the market, we must also brighten our eyes, have a certain ability to recognize, and need to be discriminated with syndrome under the guidance of a doctor.

③ Regularly review the liver function

Professor Lin Yi reminded that not only patients who have taken Chinese medicine for a long time, but in fact, patients who have taken any drugs for a long time should regularly review the liver function under the guidance of a doctor.

Drug -based liver injury is one of the most common and serious drug adverse reactions. Clinical medication should be strictly selected and valued. Although a small number of Chinese herbal medicines have a certain risk of liver injury, it should not be exaggerated too much, let alone "prefer" and "limit the surface". It is unfair to patients to give up a forest for "a tree". Professor Lin Yi pointed out that compared to "abandoning traditional Chinese medicine and abandoning any drugs that may cause liver injury", reasonable regulating medication, obeying medical advice, and regular follow -up review are the most effective means to prevent drug liver injury.

This issue

Situ Honglin

Professor, chief physician, doctoral supervisor. The second batch of national and old Chinese medicine experts Lin Yi academic heirs, deputy chairman of the Breast Disease Branch of the Chinese Medicine Society, and won the "National First Chinese Medicine Inheritance Gao Award Award" by the Chinese Society of Chinese Medicine.

Disposal time:

Monday morning: Twenty -Floor Breast Diagnosis and Treatment Center, 10th Floor, Daode Road General Hospital of Guangdong Provincial Hospital of Traditional Chinese Medicine

Tuesday morning: The Department of Breast Department, 5th Floor, Outpatient Clinic of the University of the University of Traditional Chinese Medicine

Wednesday and Friday morning: The Department of Breast Department, 2nd Floor, Outpatient Clinic of Ersha Island Hospital, Guangdong Province

Thursday morning: 5th floor of the West District of Dade Road General Hospital of Guangdong Provincial Hospital of Traditional Chinese Medicine needs outpatient clinics

Well

Inpatient, Lin Yi National Famous Traditional Chinese Medicine Inheritance Studio Assistant. Graduate graduate graduated from Beijing University of Traditional Chinese Medicine. Professor Lin Yi.

Posted by Molecular Medicine Reports, Life Science, onCology Letters, and onCology Reports magazine. Participate in 6 national natural topics, compiled 5 books, and participate in the research and development of special research and development special topics in the National 13th Five -Year Plan.

Supply: Lin Yi National Famous Traditional Chinese Medicine Heritage Studio