Knowing it, it is new with ancient!Inheritance of the theory of spleen and gastric disease diagnosis and treatment

School of Science and Technology of Chinese Medicine Sciences

Public account ID: CACMS1955

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The inheritance of the theory of spleen and gastric disease diagnosis and treatment needs to focus on verification, optimization and expansion of results based on the experience of the sages, and innovation should find key problems and needs of digestive system diseases. Under the support of multidisciplinary cross, appropriate methods, technology and technology and technology and The theory studies, interprets, and integrates, and then effectively solves the new clinical problems of spleen and stomach problems.

Inheritance and innovation are the foundation of the vitality of the cause of traditional Chinese medicine. It is of great significance for promoting the application of traditional Chinese medicine theory, exerting the original advantages of traditional Chinese medicine, improving the ability of scientific and technological independent innovation, ensuring the healthy development of Chinese medicine academic and health, and promoting the construction of healthy China. The inheritance of the theory of spleen and gastric disease diagnosis and treatment needs to focus on verification, optimization and expansion of results based on the experience of the sages, and innovation should find key problems and needs of digestive system diseases. Under the support of multidisciplinary cross, appropriate methods, technology and technology and technology and The theory studies, interprets, and integrates, and then effectively solves the new clinical problems of spleen and stomach problems.

The efficacy of improving traditional Chinese medicine is guided by clinical problems

The evaluation of "effect" clinical significance should be combined with clinical reality. For example, in the 1950s and 1960s, common difficulties such as digestive ulcers, especially duodenal gut ulcers, Chinese medicine believed that the pathogenesis was chilling for the spleen and stomach. Healing rate has cured many patients. However, with the iterative update of Western Medicine, especially the new generation of acid suppression drugs launched around 2000, a proton pump inhibitor, the healing rate of the duodenal bowel ulcer can reach more than 85%, 4 The weekly healing rate reaches 100%, and it has a very good analgesic effect; the annual recurrence rate of the duodenal ulcer infected with the pylori infection was originally as high as 80%, while the Western medicine roots can make it annual recurrence rate The drop to a few percent has gradually lost its clinical advantages in the field of gastrointestinal ulcers. Therefore, in the practice of inheritance and innovation, the evaluation of the clinical significance of traditional Chinese medicine or any medical technology effect should be combined with clinical reality to achieve subjective and objective combination.

Features are the characteristics of things inherent, and the advantage is a comparative advantage. "Give full play to the characteristics and advantages of traditional Chinese medicine" is a sentence often said in the traditional Chinese medicine industry. However, the advantages and characteristics of understanding things need to pay attention to the following points: First, the characteristics are inherent in the things itself. For example, through the collection of clinical data through looking, smelling, asking, and cutting, and judging as a syndrome of a certain nature, it is a characteristic of the diagnosis of traditional Chinese medicine. It is necessary to observe and think about the old Chinese medicine recipes with experienced old Chinese medicine. How to do diagnosis, what needs special attention, how to summarize the main symptoms, and how to distinguish it. This diagnosis method has characteristics and inheritance. The second is that the advantage is compared with other things, and is a relative comparative advantage. It does not mean that there are advantages, but there is no difference in the characteristics without features, and it is not a matter of advantage. If Chinese medicine is exactly the same as Western medicine, it will not be able to talk about the advantage. However, to achieve relative advantages, it is necessary to take out evidence of comparative effects on the basis of characteristics in order to form a true advantage of Chinese medicine and allow the entire industry to recognize. The core of tradition that the characteristics of traditional Chinese medicine are "overall concepts, dialectical treatment". While we understand the characteristics of the characteristics, we also need to implement the specific diseases. From a phenomenon, traditional Chinese medicine has potential advantages in many diseases, such as the application of fire needles and cupping therapy to treat shingles, pediatric ridge therapy to treat infant indigestion, Huoxiangzhengqi water treatment in summer and autumn diarrhea, etc. It is a long -term practice of Chinese medicine. The summary and verification of experience, but from the perspective of evidence -based medicine, it is necessary to come up with evidence of group laws, so that the medical community at home and abroad is widely recognized and promoted.

The efficacy of improving traditional Chinese medicine is guided by clinical problems. It is really valuable to study or compare clinical issues that meet the actual needs of clinical needs. For example, in the field of digestion, how to delay or reverse the progress of pre -gastric cancer lesions, how to solve the problem of pylori screw pylori resistance, how to improve the treatment effect of the overlapping functional gastrointestinal symptoms, how to treat refractory gastroesophageal reflux disease and Solve the dependence of proton pump inhibitors, how to maintain the clinical relief of ulcerative colitis and prevent recurrence, and how to prevent postoperative recurrence of colon and polyps, and in terms of the research of these diseases, what are the related scientific and technological issues and how to obtain people inside and outside the industry and outside the industry The appraisal of clinical efficacy evaluations are all issues worth thinking and research. We should grasp the accurate clinical problems, with the guidance of practically solving practical problems, centered on improving clinical efficacy, and exerting the characteristic advantages of Chinese medicine.

High -level evidence and scientific evaluation are indispensable

At present, the Chinese medicine industry is facing huge pressure and challenges in terms of evidence support. The support of clinical effectiveness cannot be satisfied with the description of effective cases and the effectiveness of patients. Multi -central random control test (RCT) evidence. In addition, it can prove that clinical effectiveness is not enough to meet the demand for scientific issues. It also needs to use modern technology to explain its mechanism in the language of pharmacological and molecular biology. The process of confirming can be summarized as the potential advantages in the phenomenon, then fully understand the advantages and scientific design research ideas, ensure the quality control in the research process, and finally obtain evidence of advantages. Explained from the following two important views.

"Effective" must be carved in depth based on clinical problems. The definition of "valid" significance must be combined with clinical science issues, technical problems, and medical service needs, and "effective" is the result of comparison. It is the identity of internal and external and outside the industry. It requires high -level evidence support. For example, my country is one of the high incidence of gastric cancer. The incidence and mortality of gastric cancer ranks at the forefront of global malignant tumors. One of the reasons is not enough attention to the screening and treatment of pre -gastric cancer diseases. The secondary prevention and management is not in place, and the center of gravity is needed to move forward in terms of gastric cancer prevention strategy, regular monitoring and early intervention. Modern medicine lacks effective means in the early days of gastric cancer diseases. Traditional Chinese medicine has shown its effectiveness in clinical practice. It is mainly because of the lack of evidence that complies with norms in the past, the lagging of the concept of disease, the lack of scientific and recognized clinical intervention schemes, and the rigorous efficacy evaluation method, and the problem of not solving the consistent positioning of mucosa biopsy before and after treatment. We did some explorations for these issues. For example, the biopsy technology that used the first reported mucosa standard at home and abroad, with a multi -center RCT research design and designing the clinical efficacy of Chinese medicine Moron, the results showed that Morrinia's treatment of pre -gastric cancer proliferation hyperplasia disappeared disappeared The rate is 24.6%and the folic acid group is 15.2%. The overall symptoms of the Moridan group are better than the folic acid group. The study was quoted by the European authority "MAPS II" by the European authoritarian guidelines, "MAPS II", which means that the efficacy of traditional Chinese medicine treatment of pre -gastric cancer lesions has received great attention from the international medical community. "Effective" must be based on scientific evaluation and quality control. How to present the advantages of traditional Chinese medicine and the advantages of traditional Chinese medicine has always been a key issue that plagues Chinese medicine researchers, and scientific research and design, standardized quality control, and clinical research support platform that is in line with international standards. Effectiveness is crucial. Due to the uniqueness of Chinese medicine theory and its compound therapy, in reality, we will encounter many research methods, tools, and standards that cannot completely reflect the characteristics and advantages of Chinese medicine. Therefore Clinical research quality management standards, improve the level of evaluation of the efficacy of traditional Chinese medicine. In these respects, we have also made some explorations, such as joint authoritative Western medicine experts to formulate the consensus of clinical application experts of gastric mucosa standard biopsy, and promote the application of key technical solutions for clinical research on pre -gastric cancer. %Of the traditional Chinese medicine soup agent placement method and establishing production and evaluation procedures; the PRO quantity table that reflects the overlapping symptoms of chronic gastrointestinal diseases, solve the professional problems of overlapping evaluation of the symptoms of chronic gastrointestinal diseases; The intestinal effects of traditional Chinese medicine compound therapy are easy to be susceptible to clinical efficacy evaluation indicators and their application weights. In addition, we have also created the "Chinese Medicine Clinical Effect and Safety Evaluation National Engineering Laboratory" as a clinical research platform. The platform includes central random systems, networked electronic medical record collection systems, quality control systems, data management systems, CAPs (China Central China The medical research ethical ethics review system) and the protection system of the American AAHRPP (American Human Research and Protection System Certification Association) certification, so that the clinical study of traditional Chinese medicine can be fully connected with the world. These are new scientific research methods and tools created by the characteristics of traditional Chinese medicine diagnosis and treatment and international scientific research standards, which provides technical support for explanation and the advantages of the curative effect of traditional Chinese medicine.

Traditional Chinese medicine thinking is the basis for the advantages of spleen and stomach theory

Effectively guiding clinical practice is the foundation of spleen and stomach theory, and inheritance is the guarantee of its vitality. The inheritance focuses on inheriting the theory of the classics of Chinese medicine, the theory of spleen and stomach physiology, the academic thoughts of important doctors, and the methods and techniques of solving the spleen and stomach disease. In -depth learning and application of these theories and technologies can help discover the advantages of solving clinical problems.

First of all, in terms of theoretical inheritance, the study of traditional Chinese medicine has a long history. How to retain its traditional characteristics, based on the development of the times and the changes in spleen and stomach diseases. The theory of Tonglin is the result of the study of the academic thought of the treatment of spleen and stomach disease in Tong Jianhua, which is quenched by Chinese medicine scientists. The theory is based on the Chinese medicine spleen and stomach. The upper descending is smooth, the pathological stagnation is the disease, and the treatment is to remove the disease "; the" two points theory "of the gastric disease regulations, that is, the" spleen and stomach "and" spleen and stomach cure "; Treatment of the stomach must regulate qi and blood. The theory of Tongxin has an important guiding role in the diagnosis and treatment of chronic gastric diseases, emphasizing that Tongtong has a effect on clinical rectification today. Rhythmic peristalsis, improper clinical problems and treatment goals when treating stomach diseases. In -depth comprehensive understanding and using the academic essence of sublimation, stagnation and disease in the theory of downshifting, and deprivation techniques of deprivation of diseases, have an important role in solving the clinical problems of spleen and gastric disease diagnosis and treatment.

Secondly, in terms of theoretical advantages, the diagnosis and treatment thinking of the overall concept of traditional Chinese medicine and dialectics is compared to Western medicine, and it is the basis for the advantages of spleen and stomach theory. The combination of disease syndrome can make traditional dialectical treatment more accurate. For example, non -erosion reflux disease, which uses the stomach content to reflect into the stomach, the esophagus mucosa visible to the naked eye under endoscopy is damaged. Inhibitory or neutralize gastric acid, supplemented by dynamic drugs, and the combination of disease syndrome treats acidity and stomach reduction in the treatment of the theory of the disease. Symptoms can also improve systemic symptoms and avoid seizures after stopping drugs. Furthermore, syndrome differentiation can solve the problem of overlapping diagnosis and treatment of functional gastrointestinal diseases. Symptoms of functional gastrointestinal diseases refer to multiple symptoms or symptoms of symptoms in the same period of the same period of the patient, including the overlapping of different diseases and the overlapping of different subtypes of the same disease. The rate of repeated visits is high. At present, modern medicine is not very satisfied with the overlapping effect of functional gastrointestinal diseases. Chinese medicine emphasizes the symptoms of upper and lower digestive tract as the manifestation of the spleen and stomach system. , Summarize its clinical manifestations as a single certificate or composite syndrome to combine the disease syndrome, in order to syndrome the disease, discriminate the treatment, and improve its symptoms while treating the main symptoms of the disease. The intervention effect has a relative advantage relative to the target of the existing traditional drug. Clinical trial research injects new connotations into the concept of traditional Chinese medicine

From the perspective of traditional Chinese medicine research, the compound Chinese medicine can be regarded as a tool and carrier of the logical argumentation of "rational-law-square-medicine". Studies, the new theory and new knowledge involved in the latter largely have a positive effect on explaining the theory of spleen and stomach and the syndrome of spleen and stomach disease. In this regard, we also made some positive explorations.

In terms of spleen deficiency theory, we first proposed the decomposition design concept of spleen main transportation and spleen, spleen mainization and spleen, and innovated the unwell syndrome and functional diarrhea after functional digestion dish. The clinical research model with spleen is not transported by the spleen, which is difficult to transfer when the spleen is not transported. It is manifested as a unsuitable syndrome after dysfunctional indigestion. The accumulation of water and wetness is manifested as functional diarrhea, poor absorption function, and has certain representativeness. It has found a symbolic clinical foothold for the macro concept of spleen. With the specific illness, it can be targeted at random, control, blind method and other evidence -based methods. The basic experiments of the inquiry mechanism can continue to deepen. Essence This study not only proved the efficacy advantage of the spleen and governance and classic spleen square agents through clinical trials, but also used metabolic group science and technology to explore the changes in energy metabolism in patients with spleen deficiency and syndrome. The network-mitochondrial system promotes gastric power. By regulating mechanical sensitive ion channels to improve high sensitivity of internal organs, the spleen and wet reciprocated can be adjusted to the water, regulate the level of ion channel, and adjust the absorption of water and fluid to regulate the energy required for ion transfer. Traditional Chinese medicine concepts such as the main transportation and spleen and the law have injected new scientific connotations.

Full Chain Research and Innovation Theory of Spleen and Stomach Diseases

The whole chain research of the theory of spleen and stomach disease diagnosis and treatment mainly includes three aspects: one is to focus on inheritance research, learn the experience of sages, and conduct theoretical consolidation; the other is to carry out evidence -based research, obtain high -quality evidence, and conduct theoretical application; How to answer the theoretical interpretation. So as to achieve the goal of innovating the theory of spleen and stomach disease, further enriching and enriching the theory of spleen and stomach. We also have the following planning and thinking.

First, the "grid to know" and build a research system for the special disease evidence library and the special patient queue. In recent years, under the support of different technologies and methods such as blockchain, real world research, big data analysis, spleen and stomach disease library and database construction, more and more dimensions of evidence data can be obtained. Relying on the China Traditional Chinese Medicine Evidence -based Medical Center Gastrointestinal Medical Center, we have built a big data platform for evidence -based documents for spleen and stomach diseases. Problems, data security compliance issues, and data technology platforms such as unwillingness, dare, or data sharing services that occur in the shortage of data technology platforms. In the future, we aims to build a joint analysis platform that is integrated, intelligent, intelligent, shared and shared by designing, registering, data exchange and transformation based on the whole process. Evidence promotes the development of traditional Chinese medicine.

Second, "new with ancient", enrich and innovate the theory of spleen and gastric disease diagnosis and treatment. In the process of inheriting the application of Tongtu Theory, in addition to grasping the basic views and methods of Tonglin theory, the thinking of Tongxin theory is implemented in the process of diagnosis of gastrointestinal diseases, so as to quickly and accurately grasp the traditional Chinese medicine disease of the spleen and stomach disease The characteristics of the machine are also an important part of the inheritance of spleen and stomach theory. After long -term clinical practice, thinking and summary, the "new eight outline" of spleen and stomach disease dialectical is an important manifestation of this inheritance innovation method. The new eight outlines of the spleen and stomach disease, which is discerning internal organs, virtual reality, cold and heat, and qi and blood. Among them, the focus of the viscera focuses on the disease position, the focus of qi and blood focuses on the new and old depths of the disease, the cold and heat is the characteristics of the diseased evidence, and the focus of deficiency and truth pay attention to the state of the body state. Essence Different from the eight scholarship, the "new eight outlines" can be diagnosed with the characteristics of spleen and stomach disease, which is an important innovation in the theoretical diagnosis of the spleen and stomach. Based on the inheritance of the traditional spleen and stomach theory and the theory of Tongtong theory, combined with long -term clinical experience, we proposed the theory of "regulating and reciprocating" for the treatment of spleen and stomach diseases, that is, advocating the cause of the spleen and stomach to rise and fall. ; "Eight Gang Tongtong Methods" and "two balances" strategies. "Treatment of the spleen eight methods" is strengthening the spleen and qi, strengthening the spleen and dampness, strengthening the spleen and warmth, strengthening the spleen and moisturizing, warming the spleen and relieving diarrhea, strengthening the spleen and softening liver, strengthening the spleen and the lungs, and nourishing the spleen and kidney; The law "is to treat stomach problems from the viscera, virtual reality, qi and blood, and cold and heat; The proposal of the theory of "reconstruction in the middle" is the inheritance and innovation of the theory of spleen and stomach, which has important practical significance and promotion value for the treatment of spleen and stomach disease in the new period.

Source: China Traditional Chinese Medicine News

Author: Tang Xudong, Chinese Academy of Traditional Chinese Medicine

Edit/typesetting: Zhang Lei

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