You can fast and precise medical test at home!The study of Wuhan University People's Hospital has won important breakthroughs

Wuhan Evening News August 3 (Correspondent Yang Cen Wu Yuqing) Without specializing in the hospital, home can be fast and precise medical testing at home. The test results are intelligent output on mobile phones: "Portable family testing of diseases" is expected to become a reality. Recently, the Molecular Medicine Research Institute of Wuhan University People's Hospital promoted cross -integrated innovation with clinical problems, and developed a portable analysis system. In order to facilitate, fast, and accurate diagnosis of diseases, a new scene of clinical application was displayed.

Published online.

The results of this research were published in the latest internationally renowned academic journal "Advanced Materials". State Jie Qing, a special professor of Wuhan University People's Hospital, Professor Yuan Quan, Deputy Director of the Research and Public Service Conditioning Platform of Wuhan University, and Professor Yang Yanbing, a national future female scientist, planned to be the author of the research communications. The Cardiovascular Hospital of Wuhan University People's Hospital (Department of Cardiovascular Department) is the first author unit and a common communication authors.

Many diseases have specific molecular markers that can be performed through the body fluids such as urine to help the early diagnosis of the disease, judge the staging of the disease, evaluate the treatment effect, and the long -term prognosis. Therefore Clinical diagnosis and treatment are of great significance. Based on this, the research team of the Molecular Medicine Research Institute of Wuhan University People's Hospital formed a cross -integration of molecular identification technology with integrated circuit technology through cross -integration and innovation, and developed a portable analysis system for rapid and accurate testing for specific molecular markers.

The portable analysis system performs real -time detection, intelligent analysis and intelligent diagnosis.

It is reported that the portable analysis system has the advantages of efficient, convenient, high sensitivity, high -specific, and can detect multiple molecular logo at the same time. Compared with the traditional detection method, the sensitivity of the portable analysis system has been increased by nearly 2 times (the detection limit is as high as 10–17g/ml – 1), which is expected to achieve early detection of the disease; Things can significantly improve the accuracy of disease diagnosis than traditional detection methods. The research team further applied the portable analysis system to clinical verification, confirming that its diagnosis of diseases for the disease was as high as 100%and the specificity was 92%, which was significantly better than the existing testing technology.

The research team further integrates the portable analysis system with the Bluetooth module, relying on the smartphone APP to develop a portable device (only the size of a smartphone), for real -time monitoring of molecular logo, automatic analysis processing data, mobile app side smart output, the entire entire The operation is simple and efficient. In the future, patients are expected to achieve a portable family diagnosis of the disease. Diagnostic information is shared with the diagnostic information to the doctor through the mobile phone to effectively reduce the patient's medical treatment time and economic costs, save medical resources, and for patients' early diagnosis, evaluation of efficacy, home health management management And the monitoring provides great convenience.

The core component display of the portable analysis system.

At present, the research related technologies have applied for a national invention patent, and medical device registration certificates are being applied. The research team plans to continue deep cultivation in the field of portable body in vitro and personalized testing to help the development of clinical diagnosis and medical industry.

Academician Zhou Xiang, an academician of the Chinese Academy of Sciences and Honorary Dean of the Molecular Medical Research Institute of Wuhan University, introduced that chemistry has a lot of actions in the field of medical fields. Establishment of molecular medical research institutes will be a good opportunity to solve clinical problems in application chemistry, which is in line with national innovation In the development strategy, the two parties cross -integrating collision sparks, producing more original scientific achievements, making greater contributions to people's health and disease diagnosis and treatment. The cooperation research by the School of Chemistry and Molecular Science and People's Hospital in Wuhan University in the field of portable analysis system research and development is another scientific exploration made by actively responding to the "cross -integration" strategy.

(Thesis link: https://onlineelibrary.wiley.com/doi/10.1002/adma.202203224)

[Edit: Yu Lina]

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