Sohu Pharmaceutical | The United States announced: Cure in the world's fourth patients with AIDS

Produced | Sohu Health

Author | Zhou Yichuan

Edit | Yuan Yue

Many websites such as MedicalXPress reported that California, Los Angeles, announced that a patient had successfully "cured" AIDS and became the fourth successful case in the world. However, this case cannot bring hope to tens of millions of viruses worldwide.

The man was diagnosed with infection in 1988. After 31 years of medication, he was diagnosed with acute marrow leukemia. Doctors used the donor bone marrow with CCR5 Delta32 rare gene mutations for stem cell transplantation. This gene can change the entrance of virus invasion of white blood cells to generate resistance. After transplantation, these cells took over the body's immune system. No live virus was found in the body in the body for 17 months of discontinuation of antiviral drugs.

There are also media reports that this is the fifth case of healing. At the same time, a patient in Dusseldorf has also been resolved. The previous three patients in the world are also leukemia patients, which have been cured by bone marrow stem cells or umbilical cord blood through special mutations.

Does AIDS mean that it can be overcome? It's far away. Experts say that bone marrow transplantation therapy is equivalent to temporarily destroying the immune system. The process is complicated and the side effects are great. No one except cancer patients need to do so. Even if they pass the approval, only 50 patients with AIDS and leukemia may benefit each year and have no feasibility.

Healing cases provide important ideas for the field of anti -AIDS, such as transmitting enzymes through CRISPR technology to enter the body to eliminate CCR5, close the gate of the virus into the cell, and finally achieve the cure target. However, tens of millions of patients in AIDS worldwide are still increasing; in the global economic underdeveloped areas, the high degree of popularity of the economy is high, and residents can not even get clean water, food and reliable medicines. Gene editing treatment is undoubtedly the night.

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