The successful development of monkey acne virus virus standard substances, which can be used to develop testing kits

The reporter learned from the Chinese Academy of Metrology Science that the institute has successfully developed the standard substances of the two pseudo -viruses of monkey acne virus wild B6R genes and mutant F3L genes. These two standard substances can be used for the development and performance confirmation of monkey acne virus detection kit, performance confirmation, method verification, and laboratory quality control. Previously, there were no standards of pseudo -virus virus virus at home and abroad.

Monkey acne is a kind of human and animal infection caused by monkey acne virus infection. It mainly manifested in clinical heating, rash, and lymphadenopathy. The main source of infection is a rodent infected with monkey acne virus. The "Guidelines for Monkey Acne Diagnosis and Treatment (2022 Edition)" issued by the National Health and Health Commission clearly proposes that the use of nucleic acid amplification detection methods can detect monkey acne in specimens such as rash, blister, scalp, or nasopharyngeal secretions and other specimens. Virus nucleic acid.

According to reports, the standard substances of pseudo -viruses launched by the Chinese Metanotection Council this time use the preparation methods, measurement methods and meter plants that meet the requirements of metrological characteristics to ensure the accuracy and traceability of its quantity value. These two standard substances provide "biological ruler" for the results of the diagnosis of monkey acne virus, thereby providing technical support to effectively reduce "false negatives".

The Chinese Metanotectional Institute uses a digital PCR method to determine the copy number concentration of the B6R and F3L genes of monkey acne virus. The characteristic amount is the copy number concentration of the monkey acne virus B6R gene or the F3L gene contained in each solution. The specific amount is shown in Table 1.

At present, many companies in China are or have developed monkey acne virus nucleic acid testing kits. The standard substances launched by the China Institute can be used as measurement standards, for the development and performance evaluation of monkey acne virus detection kits, and can also provide traceability support for the export of domestic kits.

(Chen Haibo, all media reporter of Guangming Daily, correspondent Dong Lianhua, Zhou Yining)

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