Sohu famous doctor | Professor Bei Ling Lin: How long is the gastroscopy?

Produced | Sohu Health

Author | Wu Shinan

Edit | Yuan Yue

"Our Chinese esophageal cancer is about 53%of the world, and death cases account for 55%." Professor Shen Lin of Peking University Cancer Hospital quoted data to say the severe situation facing esophageal cancer diagnosis and treatment of esophageal cancer in my country.

Half of the world's esophageal cancer occurred in China. What is the reason? Seeing symptoms to prevent reliable esophageal cancer? How long is it suitable to prevent esophageal cancer? In an interview with Sohu, Professor Shen Lin made a detailed interpretation of the above issues.

Living habits plus genetic background lead to high incidence of esophageal cancer in my country

Professor Shen Lin pointed out that among Chinese esophageal cancer patients, more than 90%of esophageal squamous carcinoma, but most of European and American countries are adenocarcinoma. The biological behavior of the two is different.

Specifically, the high incidence of esophageal cancer in my country is the impact of lifestyle habits, such as high -salt diets, eating pickled foods, mildew foods, and like hot tea. Especially the damage to smoking and drinking. Almost all patients with esophageal cancer have the habit of smoking and drinking. This has led to the incidence of male esophageal cancer much higher than women.

On the other hand, the impact of genetic background. "Esophageal cancer has susceptible genes. Henan, Shaanxi, Shanxi, Inner Mongolia, Shandong, and South China are high incidence areas. Therefore, its onset may be related to genetic background." Professor Shen Lin said.

In addition, some people have found that esophageal cancer is related to some flora in the oral cavity. These reasons show that the causes of esophageal cancer in my country are unique.

There is no symptom in the early stage, preventing the gastric and esophageal mirror

All cancers are advocated "early discovery", but there are almost no symptoms in the early stage of esophageal cancer. Professor Shen Lin said that among the patients who came to the doctor, the most common manifestation was poor swallowing, difficulty swallowing, and a foreign body sensation. In fact, when some patients have not showed difficulty swallowing, they are already in progress. If you want to treat early and treat it early, you need to perform regular esophageal mirrors or gastroscopy.

There are high -risk groups of risk factors such as family history of esophageal cancer, family history of tumor, and dangerous factors such as smoking, drinking, and drinking tea. If you find a typical hyperplasia or scale -like epithelium hyperplasia, be careful. If the hyperplasia is obvious, an endoscopic examination may be performed every year.

If it is a healthy crowd and the test results of the previous gastroesophageal mirror are normal, and there is no organic change, it can be checked every two to three years.

"The doctor will inform the review time according to the patient's situation. But it is also necessary to avoid excessive fear. It is not necessary to check the gastroscopy every two or three months." Professor Shen Lin reminded.

There is no breakthrough in advanced treatment methods for many years, and new plans need to be urgently needed

Since it is difficult to prevent early, treatment is particularly important for patients with esophageal cancer. But unfortunately, the curative effect of the treatment of advanced esophageal cancer in my country before is still unsatisfactory, and the treatment methods are very limited.

Professor Shen Lin said that in the past few decades, we only have the two types of chemotherapy (5-FU) and cisplatin chemotherapy for the treatment of drugs, and the median total survival period brought in less than one year. The demand is not met.

In the past year, the news that immunotherapy has made breakthroughs in advanced esophageal cancer, especially esophageal squamous carcinoma. Among them, the PD-1 inhibitor Nawuli Mipida+chemotherapy was treated in the country in China, which brought more treatment methods to doctors.

How to evaluate the impact of immunotherapy on the treatment of esophageal cancer? Professor Shen Lin gave three keywords: "breakthrough", "hope" and "promoting".

"'Breakthrough' refers to the emergence of immunotherapy, breaking through the treatment difficulties and bottlenecks of esophageal cancer in the past 50 years; 'Hope' means that it brings the hope of survival to patients, and it also brings more treatment methods to doctors. Hope; 'Promoting' refers to immunotherapy that promotes our understanding of esophageal cancer, has aroused more researchers' interest in esophageal cancer, prompting us to further explore the mystery behind esophageal cancer, and bring the hope of cure for more patients to bring more patients with healing. . "Professor Shen Lin concluded.

At this stage, more and more enterprises in gastrointestinal tumors have been deployed at home and abroad. Taking Nawuoli as an example, in addition to the first -line therapy of esophageal squamous carcinoma, it also covers a number of adaptive diseases such as esophageal cancer treatment and first -line gastric cancer treatment.

"This shows that multinational companies are also paying more and more attention to the predicament of our Chinese people." Professor Shen Lin said, "If the world is here to pay attention to the needs of our Chinese patients, I believe that the future treatment of our esophageal cancer and gastric cancer It will be better. There will be more treatment methods and effective drugs. We also look forward to the arrival of this day. "

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