Happy report!Fudan University broad -spectrum new crown MRNA mutation plant vaccine obtained clinical trial approval

The "New Coronatte Virus Mutant MRNA Vaccine (S Protein Chimi)" jointly developed by Fudan University, Shanghai Bluebird Biomedical Co., Ltd. and Yunnan Watson Biotechnology Co., Ltd., has received clinical trials issued by the State Drug Administration Approval. Lin Jinzhong, a professor at the School of Life Sciences of Fudan University and Director of the MRNA Pharmaceutical R & D Center of Fudan University, represented the entire R & D team to the pre -clinical research report of the vaccine to the Pharmaceutical Review Center of the State Drug Administration. This milestone marks important results in the integration and innovation path of multi -party cooperation and industry -university -research integration of Fudan University.

Professor Lin Jinzhong began to develop MRNA new crown vaccines in February 2020, and he soon achieved excellent immunology effects in animal research. The results were quickly published and listed as a global candidate for the new crown vaccine. Entering 2021, in the face of the continuous and repeated epidemic, Fudan University, Bluebird Biological and Watson Biological Industry, Graduate, Research and Research Integrity and Give full play to their respective advantages. On the basis of the previous work, they further developed a broad spectrum based on the new coronary virus S protein. The MRNA vaccine of the new crown variants, and the first of which uses the chimeric antigen design. Through the difficult joint research of more than a year, the breakthrough of the key core technologies of the vaccine research and development and production is achieved. Studies have greatly promoted the development of MRNA vaccine technology in China.

Since the outbreak of the new crown epidemic, Fudan University has not stopped for a moment in the face of epidemic research research. The school's experts and researchers are running against time to actively organize and carry out various epidemic prevention and control scientific research projects, which provides a strong strong for the prevention and control of the epidemic situation. Powerful scientific research support. Fudan University is one of the earliest colleges and universities engaged in RNA foundation and application research in China. It has made a long time in the MRNA drug research. The "MRNA Drug R & D Center" was established in the school. "Zhangjiang MRNA International Innovation Center". With the care and support of the Ministry of Science and Technology, the Ministry of Education, the Shanghai Science and Technology Commission, the establishment of the Shanghai Science and Technology, Xie Ming school, and the people of all parties, Fudan University is trying to create a research system covering the MRNA basic research, MRNA platform and MRNA application, which has gathered to condense A professional research team provides technical support and platform guarantees for my country's MRNA technology and provides technical support and platform guarantees for my country's biological safety prevention and control.

Source: School of Life Sciences, Institute of Science and Technology

Responsible editor: Wang Yiyi

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