"Xun Yuanhua New" Exhibition: He has developed the first new drug to be imitated by the United States

On July 10, 2022, the third "Suzhou Scientist Day". The "Xunxinhua New: Xie Yuyuan" exhibition "Xunxinhua New: Academician of the Chinese Academy of Sciences" sponsored by Suzhou Public Culture Center (Suzhou Celebrity Museum) and the Shanghai Institute of Drugs of China. After more than a year of preparation, the exhibition was fully supported by Academician Xie Yuyuan's relatives and work units in the three places of Beijing and the Soviet Union, and the alma mater. It exhibited 60 pages of handwriting, 109 old photos, 6 sets of experimental devices, 38 chemical instruments and models 37 certificates, 96 ancient books, newspapers and other physical materials, and 83 precious documents such as transcripts and classmates, showing Xie Yuyuan's 70 -year -old and fruitful life.

Xie Yuyuan (1924-2021), from Suzhou, Jiangsu. Pharmaceutical chemistry and organic chemist, researcher and former director of the Shanghai Institute of Pharmaceutical Research, Chinese Academy of Sciences. Due to the needs of the country's needs to change the direction of scientific research, it has achieved major results in many scientific research areas such as the full synthesis of natural products, the radioactive nuclear -promoting drug research, and the civil development of medical chelating agents. In 1991, he was elected as a member of the School of Chinese Academy of Sciences (Academician). The name of this exhibition is "Xunxinhua New", which is to try to summarize the path of academicians to explore the origin, develop new drugs, and benefit the society in the field of pharmaceutical chemistry and organic chemistry.

exhibition site

In April 1924, Xie Yuyuan was born in an official home in Beijing West Fourth Bingma Hutong. Born in Beijing, rooted in Jiangnan. Xie Yuyuan's father Xie Jing was a native of Wu County, Jiangsu. He was the Director of the Department of Politics of the Ministry of Communications. When he was in the heyday, he returned to his hometown and returned to his hometown. When he was young, Xie Yu often followed his father to go to the old book before his old school. He also read literary and historical masterpieces such as "Ancient Literature Perspective" and "Gang Jianyi Zhi Lu" under the guidance of his father, and gradually became interested in literature and history. When he was in college, he wanted to choose literature or history, but he was resolutely opposed by his father and brother. The father and brother started from the idea of ​​saving the country in the industry and believed that studying science and engineering was the way out. At that time, two brothers studied immunology and one specializing in earthquakes. At the suggestion of the two brothers, Xie Yuyuan chose to learn chemistry after some thought.

Tsinghua University transcript

In 1940, Xie Yuyuan was admitted to the Department of Chemical Engineering of Soochow University (Shanghai School). Unfortunately, in 1941, the Pacific War broke out. The Japanese army occupied the concession. The school could not go on. It could only drop out of school at home. It only studied at Soochow University for one and a half years. In 1946, Xie Yuyuan was admitted to the Department of Chemistry of Tsinghua University and continued his studies as a class student in the second grade. Xie Yuyuan's study at Tsinghua University has been well exercised. After graduating in 1949, he graduated with the first grade of the department to stay in the school as a assistant.

exhibition site

In February 1951, Xie Yuyuan returned from Beijing to Jiangnan. Since then, he opened his seventy -year scientific research career at the Shanghai Academy of Sciences. At the beginning of the employment, Xie Yuyuan was engaged in the research of Chinese herbal medicine chemical composition and the simple synthesis of organic matter under the guidance of Director Zhao Chengzheng. In the early days of liberation, my country was working on a large -scale prevention and treatment of blood -absorbing diseases. At that time, the only medicine that could be used at that time was liquor acid potassium (commonly known as "spit liquor"), but its toxicity was very high, and many side effects would even cause death. Therefore While preventing and treating drugs, detoxifying drugs of tadpoles should be found. In 1954, Xie Yuyuan synthesized a compound that was able to combine strongly with 锑 — di -pyramidicine and its sodium salt. After studying the pharmacological room research, it found that it was very important to eliminate heavy metal elements such as the human lead, mercury, arsenic, and 锑 锑 锑 very much. Good role, in 1958, through clinical trials. The medicine later played a huge role in the rescue of a arsenic poisoning accident. In 1991, Erji Kidinic acid was imitated by Johnson & Johnson and was approved by the US FDA to treat children's lead poisoning. This is also the first new drug in the United States to imitate China invented.

Deputy Dr. Degree Certificate

In 1957, Xie Yuyuan was selected to study abroad at the Institute of Natural Organic Compliance Chemistry of the Soviet Academy of Sciences and studied under Academician Smiajing. In 1961, Xie Yuyuan completed a highly difficult but popular topic at that time- "Fully Synthetic of Tetth Classes Antibiotics". The paper passed the defense and was awarded the deputy doctoral degree and returned to China.

exhibition site

Xie Yuyuan returned to the Institute of Drug Research of the Chinese Academy of Sciences and served as the deputy director of the antibacterial room. As the leader of the project, he planned his own laboratory, led the team to carry out scientific research work independently, and carried out a well -synthetic research of natural products that were very difficult at that time. Since 1966, Xie Yuyuan has accepted the national summons and resolutely turned to design the world's worldwide scientific research difficulties. Since 1980, Xie Yuyuan has led the subject combination to become a metal poisoning occupational disease and uranium compound "bispagoline", which once again stood at the forefront of the world in the field of professionalism. In the tide of reform and opening up, he cleverly transformed the results of chelating agents for many years, benefiting many fields such as industry, medical care, and agriculture.

Elected as a member of the Department of Studies of the Chinese Academy of Sciences (Department of Chemistry)

In 1984, Xie Yuyuan, the year of Huajia, served as the third director of the Shanghai Drug Research Institute. After 1988, Xie Yuyuan successively served as the director of the Academic Committee and the director of the National Key Laboratory. Because of his outstanding contributions in the field of pharmaceutical chemistry and organic chemistry, Xie Yuyuan was elected as a member of the Ministry of Chemistry (Academician) of the Department of Chemistry of the Chinese Academy of Sciences (academicians) in 1991. On the road of scientific research, there are endless honors. From left to Xie Yushou, Xie Yujin, Xie Yuyuan

This exhibition is particularly worth mentioning is the "Xie Liang Xie's Family" section -it turns out that Xie Yujin, Xie Yushou, Xie Yuyuan Xie's family three brothers, from childhood to their father through the wishes of the world, listen to the teachings of science and technology to report to the country. The perseverance of perseverance, in the respective scientific research fields, seemed to be diligently and continuously developed, laying the cornerstone for the development of the New China scientific cause. The second brother Xie Yujin (1913-1983) is an outstanding microorganism immunologist in my country. He dedicated his life to our country's medical sciences and seek health for millions of people. The third brother Xie Yushou (1917-2013) is the founder of the famous earthquakers and engineering earthquakes in my country.

This exhibition is a special exhibition of Suzhou Celebrity Museum in Suzhou Celebrity Museum in Suzhou Celebrity Essence It is reported that this exhibition will last until August 28. Parents in Suzhou can take the children to feel the academician style during the summer vacation.

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