The Tiandong Project was tried in October and is a major national scientific and technological infrastructure. It is located in Lizhou, Hebei

Recently, it is learned from the Langzhou Teaching Experimental Field of China Agricultural University that the models and genetic research of animal phenotypes and genetic facilities built here are progressing smoothly. Fire protection, energy conservation, earthquake resistance and archives and other special acceptance acceptances are expected to enter the trial operation in October this year.

Model animal phenotypes and genetic research have completed the completion of the construction of fire, planning, lightning protection, energy -saving and other special acceptance and completion acceptance of civil surface, and the completion and acceptance of civil construction. The picture shows a bird's -eye view of the project. Photo by Li Shuo, a correspondent of Hebei Daily

Model animal phenotype and genetic research projects are also known as Tiaopong Project. In August 2019, the construction was launched in Lizhou City, Hebei Province. It is one of the 16 major scientific and technological infrastructure that is prioritized during the "Twelfth Five -Year Plan" period. The project was the competent department by the Ministry of Education and the Chinese Academy of Sciences, respectively. It is reported that with the rapid development of the research of genomics, apparent genomics, transcription groups, protein groups, and metabolic group studies, the status of various experimental animals in the field of biomedical research is undergoing drama. The precise metering and measurement of the pattern of the model of the animal is an important bottleneck that analyzes the laws of life, researching the method of disease control, and an important bottleneck that needs to be broken. No matter from the aspects of organizational organs, physiological regulation, behavioral mode, and genetic regulation mechanisms, pigs are very similar to humans. They are an important model of research on cardiovascular disease, metabolic diseases and organ transplantation that are currently recognized internationally. As a large -scale model animal, pigs are important references and live samples for studying the laws of human life activities. They are a new way to break through the bottlenecks of animal research in the existing model.

According to Zhang Shuchuan, director of the Animal Facilities Construction Office of China Agricultural University Model, this project will support pigs' research on human disease models, organ transplantation, drug evaluation, molecular breeding, etc. At present, scientific researchers have obtained human disease model pigs such as atherosclerosis, polycystic kidney, congenital myocardial hypertrophy, etc., and developed a solution to solving genome selection of low -depth sequencing genetic typical division of genomes. Basic research, analysis of disease mechanisms, creation of heterogeneous organ, innovation of germplasm resource innovation. Zhang Shuchuan said that the phenotype and genetic analysis around the pigs, the significance of answering major questions about human life sciences, ensuring human health and meat supply, promoting high -tech development and transformation of medical research, etc. Independent innovation and enhancement of international competitiveness play a major support role.

The total construction area of ​​the project is 29982 square meters. It mainly constructs four experimental systems including animal production and cultivation systems, phenotype analysis systems, genetic analysis systems and information processing and intelligent automation management and control systems, as well as related auxiliary facilities and civil engineering projects. The main buildings include the construction of genetic experimental buildings, pig watches and experimental buildings, breeding animals, isolation quarantine houses, power station buildings, sewage treatment stations, water pump rooms, etc. After completion, 20-40 new genes or clear functions will be obtained in the year; more than 10 types of animal models of genetic modifications are available; the effective evaluation of the effectiveness, poisoning, and rationality of not less than 20 candidate drugs in the annual annual sharing; 10-20 resources; 50-70 patents applications and authorized annual applications and authorizations will establish my country's leading position in the field of animal table models and genetic research in the international model, promote the transformation and application of cutting-edge technology research results in related fields, and serve universities The overall development of scientific research institutions, pharmaceutical institutions and enterprises has good economic and social benefits.

Source: Hebei Daily Client

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