Scientists find magic elements, have you rescued your bald head?

Recently, many media have reportedly reported that Sino -US researchers have discovered a signal molecular SCUBE3 that can stimulate the growth of the head. Further researching its mechanism is expected to help people get rid of the trouble of hair loss. As soon as this news came out, it immediately attracted the attention and discussion of netizens. Many netizens even said: I can't hold my hair without starting clinical experiments.

In fact, theoretically, this new molecule does not solve all types of hair loss, but only has the effect of hair loss caused byrogens. In this article, we will introduce various knowledge related to hair loss in detail. At the same time, it will also explain how the newly discovered Scube3 molecules promote hair growth. No matter if your head is bald or not, it is not wrong to plan ahead! Come and see.

Whenever, health hair follicles are the most important

(Image source: Veer Gallery)

The growth rate of hair is 0.27-0.4 mm per day, which can be calculated that it is about 10-20 cm a year. The growth rate of hair is related to various factors, and is closely related to gender, age, and seasonal. The growth cycle of hair can be divided into three stages: growth period, retreat and rest period. Among them, the long-term is 2-6 years, the retreat period is 2-3 weeks, and the rest period is about 3 months. The growth period of the hair is also called a growth activity period, which is active. For those with normal hair volume, the hair at this stage accounts for 85%-90%of the overall.

The hair retreat period is also called atrophy or degradation period. At this stage, active hyperplasia stops, accounting for about 1%of the total hair follicles. The rest period of the hair is also called the static or rest period. At this time, the hair follicles gradually shrink, accounting for about 10-15%of the total hair follicles. Under normal circumstances, the growth, degradation and rest of the hair exist at the same time. The pulling during sorting out will promote the hairstyle that has been resting but has not yet fallen off. Under normal circumstances, people may have 50 to 100 hair fall off every day, which is physiological hair loss without too much worry. But if you continue to take more hair loss than this number, you need to pay attention.

In the composition of the hair, what is really vibrant is the hair follicles at the root of the hair. From the absorption of nutrition of the hair nipples, to the internal and external hair root sheath transportation nutrients, and the sebaceous glands provide a protective barrier. The hair follicles are like a natural "nutrition bag". Through a series of internal operations, the hair is constantly injecting vitality into the hair. Generally speaking, new hair follicles are not reappeared after adulthood. When the hair follicles are shrinking or blocked, the hair of hair, dullness, bulls, dandruff and other problems such as hair follicles emerge, so the care of the scalp hair follicles must not be ignored!

Let's see how it is "abnormal hair loss"?

Many people now have hair loss. Asians have an average of about 10 to 150,000 hair, each hair is in different growth cycles at the same time. During the resting stage, the "normal drop" hair will be covered by the white keratin structure at the root of the hair, showing a ball -like appearance.

However, if the hair is dropped during the growing period, it can be seen that the roots are soft and the shape is bent, and black tissues are often attached. Because the early hair loss is not obvious, it is difficult to notice whether you are physiological or "bald" precursor. When you notice that the amount of hair is reduced, most of them are because the hair has gradually been found to have been unable to cover the scalp. ), Or the grabbing hair is no longer thicker. At this time, it is difficult to remedy again, because the shrinking of hair follicles is irreversible.

(Picture source: Author)

Once the scalp starts to become unhealthy, the following situations may be warned to warn you:

1. Increased hair volume

2. The scalp visual range becomes larger

3. The hair is fragile and thinner and soft

4. Hairline backward

There are many reasons for hair loss. Only by finding the reason for you can you "take the right medicine"

Hair loss can be simply divided into scar hair loss and non -scar hair loss. Scar hair loss is permanent hair loss caused by inflammatory diseases. Scar hair loss is relatively rare in clinical practice, and treatment is mainly controlled by controlling inflammation. Non -scarning hair loss is divided into local hair loss, morphological hair loss and diffuse hair loss.

The scope of local hair loss is mainly "local", and round bald (also known as alopecia areata, commonly known as ghost shaving head) is the most common cause. Type -based hair loss means that the range of hair loss has a certain type, androgen hair loss and female androgen hair loss are the most common causes. The scope of diffuse hair loss covers the entire scalp. The most common is the resting period and metabolic abnormal hair loss. The cause is mostly due to excessive weight loss or pressure. During the rest period, the return of the postpartum hormonal return to the normal level led to enter the rest period and thus lose a large number of hair loss.

Alopecia areata photo (picture source: Wikipedia)

Among all hair loss, the most common is the male hormone hair loss. The male hormone hair loss has a specific scope of hair loss. Generally, the M -shaped retreat will be presented from the place where the hairline is. It gradually affects the middle of the forehead and slowly expands the scope to the top and the hair rotation. Some people will be affected first from the top and the place where the hair rotation, and the condition of the hairline is not so obvious. As for the back pillow, it is usually not affected. Here I sell a small pass, and I will tell you later.

Why does the male hormone hair loss occur? Most of the male hormone hair loss has nothing to do with living habits such as late sleep and spicy food, and has an absolute relationship with genetic. In addition to the inheritance of the patriarchal, the proportion of maternity inheritance is also very large, but mothers are usually asymptomatic. They often ask the grandfather and eunuch whether there are male hormone hair loss in order to be true. The cause of male hormone hair loss, modern medicine explains that the metabolic products of the male hormones in the body will attack the hair follicles by the male hormones distributed on the hair follicles, which will affect the synthesis of hair protein. If there is no interventional treatment during this period, the final result is that the growth period of the hair follicles is getting shorter and shorter, and the hair is too late to change, and the long thickness will enter the rest period and then fall. This process is called hair follicle atrophy. Therefore, the appearance of the male hormone hair loss will be "fine hair, large spacing, and poor scalp effect."

Mine -hormonal hair loss (picture source: Wikipedia)

The occurrence of male hormone hair loss is closely related to male hormones, so disease signs may begin after puberty. In particular, the male hormonal receiver is not evenly distributed in the entire scalp. The concentration of the front forehead and the top is higher, but the concentration of the back pillow is low. Therefore Most of the hair is still healthy. Therefore, the most common "Mediterranean" hairstyle of baldness is like this.

What is the way to treat hair loss?

At this time, everyone will ask: hurry up! How to treat "head bald"? Intersection

Researchers have long found that in the process of hairy growth, hair nipple cells play a key role. Mao nipple cells are located at the base of the hair follicles, which is of great significance to the growth and development of hair follicles and maintaining hair growth. The raw molecular "Scube3" discovered this time is a signal molecule found from hair nipples. The so -called signal molecules can understand it as a "preparation soldier" in the cell. Many times, only the cells receive instructions can the cells split, grow and even apoptosis.

The Sino -US joint research team found that at different stages of the life cycle of the hair follicles, hair nipple cells can send different signals, and the role of these signals is not the same. Essence Interestingly, the SCUBE3 signal molecules generated by the naturally produced by hair nipple cells are a "preaching soldier" that "tells" the adjacent hair stem cells.

Previously, people had conducted too many years of research on hair nipple cells, and they also clearly knew that they played a key role in regulating the growth of hair follicles. However, the signal molecules that stimulate the growth of hair follicles from it have not been clear. The Scube3 discovered this time is exactly such a activist, and its existence is obvious in the growth state of the hair follicles.

Among the hair nipples cells of male hormone hair loss, the number of activated molecules such as SCUBE3 decreased sharply, and the number of activated molecules such as scube3 decreased sharply, and the hair follicles will gradually shrink. At this time, if you can intervene in time, it is expected to restore the hair follicles function and let the hair re -germinate.

Unfortunately, although the general public urgently hopes to get the redemption of "magic elements", it has to be said that the development of drugs and therapies is a long process. We may not be able to see the relevant new drugs in the short term. It should be noted that once the hair follicles die completely, they cannot regenerate, so they should seek medical treatment in time in the early stage of hair loss.

Produced: Popular Science China

Author: Zhang Yan (Ph.D. in Physiology)

Producer: China Science Popularization Expo

references:

1. Hedgehog Signaling REPROGRAMS HAIR FOLLICLE NICHE Fibroblasts to A Hyper-Activated State

https://pubmed.ncbi.nlm.nih.gov/35777353/

2. The potential solution of the male hormone -derived hair loss: trace injection scube3 protein

https://www.163.com/dy/article/hbjuno1c0511dc8a.html

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