Can the "black history" in my mind be deleted?How to modify memory?

Review expert: Yin Tielun

Deputy Chief Physician

In the American drama "Vampire Diary", the heroine Nina chose to eliminate all the memories of the lover in order to avoid pain after losing their love; in the science fiction movie "Moving the Soul City", humans become experimental specimens controlled by aliens, and the memory will be in Clear when I fall asleep every day. In real life, some people survived under accidents, but lost their memory for several days or years. We can't help but want to ask, can human memory really be modified?

Source 丨 hippopx

How is memory stored?

Before discussing this issue, we must understand how to store memory?

Memory storage is similar to a computer, which stores abstract information by changing the physical properties of the brain. We learned high school biological classes. Human information relies on the synapses between neurons to pass, and the brain is stored to store information by re -arrange the synapses. This concept was initially proposed by neurologist pioneer SantiaGo Ramóny Cajal that in the next 130 years, scientists have been exploring various methods to try to reveal the connection between memory and human physiological structure.

Source 丨 Wikipedia Encyclopedia

The human body is a life form of cells and cell products. Nervous cells and other cells that recognize human five feelings and react to the reaction are not similar. Nervous cells are composed of two parts: cellular and protruding, and they look like germinated onions. There are some "furry" synapses on the surface of the cellular body, called tree dendrites; long parts like onion seedlings are called bearing. The synapses between nerve cells approach each other, and the neurotransmitters are stored in small bubbles at the end. When transmitting stimulating information in nerve cells, a synapper corresponding to the neurotransmitted neurotransmids to the nerve cells of the nerve cells of a nerve cells are released to the nerve cells.

Now, a new study of a new study of the synapses of synapses before and after the formation of zebrafish memories is marked with fluorescent protein. Instead, there are more synapses in some areas, and some areas reduce a certain number of synapses. The brain changes the circuit of neurotransal flow by changing the distribution of synapses, thereby achieving the effect of storage or deleting memory.

Source 丨 Baidu Encyclopedia

There are many categories, happiness, sadness, fear ... some of the past fragments that can be printed in our minds from time is to be linked to some stimulus signals. When you smell the softener that you haven't smelled for a long time, you may think of the elementary school time you play wildly many years ago; when you hear a specific melody, you will make you be in the scene when you first hear it for the first time when he hear it. Essence This information is like a lead to help us connect specific memories and emotions. In the brutal wild animal world, this method of memory storage is particularly important because they can help animals react at the fastest speed in similar scenarios, avoid danger and retain life.

Source 丨 Wikipedia Encyclopedia

However, some of the brutal encounters of human beings have strong accidents, such as car accidents, wars or other disasters. When the daily scene is linked to a huge panic or nightmare -like memory, this "information lead" will turn into a heavy chain in our daily life, which makes them unable to carry out normal life, that is, they suffer from PTSD (after trauma should be Dorisher).

Source | pixabay

At present, the main treatment method for PTSD is to keep patients in an environment that is harmless but triggers related memory, and indirectly changes the brain's synapses of the memory of this paragraph to achieve the role of patients' memories of trauma memory. However, patients receiving this therapy often recur, indicating that the trauma memory of this paragraph is still in the mind of the patient and has not been removed or modified.

Modify the possibility of memory

Is there a better treatment method that can fundamentally change the patient's memory? Maybe it is really possible. Researchers Jun-Hyeong Cho and Woong Bin Kim who use neurons and conduction as a scientific research direction are trying to study related treatment methods.

The key to this treatment lies in optical genetic technology, a technology that combines optical, genetics, software control, and genetic operations. Optical genetic technology can accurately control the activity of cells in space and time, and can control the activity of a specific morphological neurons in the brain without affecting other neurons. With this technology, scientists can investigate neurons related to specific memory and further fine -tuning.

Source 丨 hippopx

In the experiments conducted by the two researchers, they first asked the mice to hear treble and bass, and then let the mice touch the mouse in a slight current in the treble environment. After being shocked, the mouse will show "freezing behavior" when hearing the treble, but there is no response to the bass, which indicates that the storage of memory can be associated with some five -sense signals. However, the neurons in the brain are mixed with bass. Cho and KIM uses optical genetic technologies to reduce the connection of synapses and remove the mice's fear of the treble.

Source 丨 hippopx

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