380,000, a clone of a pet

In 2018, I living in Shanghai

Dial a "worth 380,000" phone,

Determine to clone the puppy Nini, who had accompanied him for 19 years.

Before she,

Most of the domestic clone dogs are police dogs, star dogs or medical dogs,

She took a different path:

Konni was regarded as "family" Nini.

2019,

This news explosion network of "380,000 clubb loves for a solitary girl",

Followed by endless curiosity, support, questioning, and criticism.

In the first half of this year, a visit was visited,

I lived with a cloning dog Nini for a day.

She said, she did not regret this choice in 3 years,

But it has also experienced more controversy than expected

—— From family, strangers and networks.

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The first generation of cloning dog Nini and the owner 玥 玥

We interviewed relevant experts at home and abroad in the form of emails,

Try to understand the significance of the technology of continuous development of cloning.

In a broad sense, have humans have become part of natural choices?

In a narrow sense, is it a reasonable love or a obsession to choosing cloning love? Native

Written article Chen Weiqin

Editor Chen Ziwen

The moment we knocked on the door, we heard the two small claws scratching the door. This urgent welcome seemed particularly cute. After opening the door, Nini rushed quickly and stunned everyone in detail. She didn't call when she saw a stranger, but instead circled around her feet.

My subconscious idea is "Will it be a cloned dog, so it is particularly good?" Then, this view was denied by the owner, "Xiao Nini's personality completely inherited Lao Nini, docile sticky. "

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Today's little Nini

Three years ago, Jun, who lived in Shanghai, chose to cloning the 19 -year -old pet dog, which became the first batch of clone dogs in China. Extracting a nail -sized skin on Lao Nini's hind legs. After the end of his life, a little Nini, with the same gene, returned to his side. Internationally, a total of three countries have supported commercial pet cloned -South Korea, the United States and China. In China, more than 20 cloned dogs similar to Nini are born each year.

At present, in addition to providing cloning, pet cloning mechanisms also have liquid nitrogen to save pet cells and pet gene testing and other services. It also plans to clone famous horses and even endangered animals. In the future, artificial intelligence is considered to transplant the original pet's memory to cloning body.

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The most conspicuous place in the refrigerator at home, with old Nini’s photos and two refrigerators made based on its image

When Lao Nini was nearly 18 years old, Ji Yan received its medical examination report, and various organs had some symptoms of failure, indicating that it may be about to leave the world within a few months.

"But it has experienced maturity from puberty to maturity, and I have not prepared to welcome death."

In 2018, I suddenly remembered an international news. American singer Barbara Studuishan cloned for 15 years. After looking for this report again, she discovered such a story: Sammie had a small habit during his lifetime. When he was happy, he would walk away. When Shi Cuishan went to pick up a clone puppy, they (3) were running towards her in the same attitude.

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In the mobile phone, there is a "Old Nini" exclusive album

At that time, she immediately called the Korean institution to perform the operation. The price asked was $ 100,000. "I felt a bit expensive. When Baidu found out that pet cloned in 2017, it was legal in China. The offer is 380,000, I think it's great, this is my last straw. "

After receiving the illness notice from the pet hospital, she contacted the veterinarian of the pet cloning institution. She still remembered that the doctor only extracted a small piece of skin at the time, put it in the saving solution, and the wound did not even produce blood. A week later, the agency's feedback was successful, and there were many living cells, which could be cloned at any time.

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As Lao Nini died, I placed it in the best place in the sun at home

In August, the day Nini left was one morning, and she breathed a large mouth in ten seconds. She endured her tears and put it under the sun and gently stroked it. "My sister really loves you, thank you for accompanying me like this For a long time, I hope you can come back again. "A few seconds later, she felt Nini walking peacefully.

On the same day, she called the institution, "Yes, do you do it," and then contacted the cremating person to send Lao Nini, "I still told the crematories on the car, it is going to be cloned."

With sadness, she went to Yunnan to support it. At that time, she was exposed for the first time with cloning, and a reporter kept calling her. She sat on the playground every day after class and repeatedly telling how Nini died and took live cells. All savings. During that time, she had a lot of emotional ups and downs, and she had experienced human flesh on the Internet.

In the past three years, I have become a complete copy of the cloning: Xiao Nini has a large blood vessels on the eyes of Xiao Nini, which is in the same place as Lao Nini's birthmark; The frequency is the same (the sound of the dog is ever -changing as the voice of a person); especially in each late night, it will use a back to a state of seamlessly fitting with the body curve of the 玥 to fall asleep. Lao Nini has the habit of it.

"It lying on my side to breathe, snoring, shouting, and jumping every day. I know it is not the original one, but it is 100 % certainly to be separated from separation anxiety and death." ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲ ▲

Scientist conducts a cloned experimental source: New York Times documentary

The cruel thing is that we cannot ignore the "surrogacy" phenomenon in the clone.

Callery is asexual reproduction. The staff rushes out of mature eggs from the mature female dogs, removes the in vitro, and then transplants the embryo into the uterus of the surrogate dog.

In terms of current technology, the cloning process is imperfect. The early stages of cloning technology need to extract 30-45 oval mother cells from the surrogacy dogs. Each experiment requires at least 2-3 surrogate dogs to surrogate to ensure the success rate.

Because of strong disease resistance and high affinity, Big dog has become the most internationally recognized experimental dog. According to regulations, each experimental dog can only be a surrogate mother once in her life, but even if she completes her mission, this surrogate mother still has to continue her "drug experiment" mission. Essence

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In 2018, body cells were extracted from Lao Nini's body

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Nini's surrogate mother

I saw Nini's surrogacy dog ​​because of a business trip. At that time, Xiao Nini was still in the stomach of the surrogate dog.

In the clean laboratory, a good Big dog was raised. Under the leadership of the staff, he saw the surrogate Nini Big dog. It was quietly nesting in a cage, more like experiments. He wore disinfected gloves and put his hand into the cage. It stretched his head and nestled on her hand. At that moment, she felt her selfishness.

The staff also added that for those who like to raise pure dogs, they may not know that all pure -breed dogs have gone through the step of "egg punching", which is similar to the process of cloning.

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Pet cloning operating table photography: Thomas Prior

At the same time, because dogs are multi -fetal animals, it is not unusual for a surrogate dog to have a few babies. In most cases, in order to control the cost and ensure the success rate, the laboratory will deliberately do a few cloned.

This experiment that emphasizes success rate even covers price games. Different institutions will give different packages, such as "second half price" or "signing the contract at the beginning. "Go", the owner of the clone dog faces a more complicated life choice than they think.

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Cloned dog photography: Thomas Prior

Take the cloning of Xunyu as an example. After confirming the cell activity, the staff persuaded her to have two Big dogs at the same time because Nini was an elderly dog. In the future, she may usher in two "Nini". (But the staff also emphasized that cell activity is not directly related to age).

Unfortunately, shortly after leaving, I received the information from the staff: one of the Big dogs absorbed the embryo, which was abortion. In the end, only a clone dog came to her.

Another elegant puppy Mimi, the owner of a cloned dog, died of an accident. She chose a Korean clone institution. In the end, the surrogate dog gave birth to two puppies. The institution also gave her a choice: Do they take it home? Although Wen Ya only wanted to get a cloned dog at first, she couldn't imagine what the other would go through the future, and finally chose two to take away.

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The sensational cloned sheep Dolly, only 6 years of the source: New York Times documentary

In the scientific community, pet business cloned has also been questioned, mainly because of the "premature failure" of cloned bodies. Is it short -lived animals?

The most famous case is the world's first cloned sheep Dolly. It died in just 6 years, and it was half of a normal sheep's life. Its survival is more like a continuation of life, not the beginning of life.

According to Li Tianli, an associate professor of the Chinese University of Hong Kong, the younger the cells used for cloning the younger the better (the ewe that provides genes with genes is 6 years old), and the clone with a certain age cells is used. Flawed. In this regard, the staff of the cloning service provided by the crickets explained that the cells have the ability to "re -edit" and can return to the beginning. And Dolly is just a case. Dolly has 4 cloned descendants. According to the research results published in the magazine published in Nature, these four cloned sheep are as healthy as other sheeps of the same age.

So far, no scientists can give clear and reliable conclusions on "whether clone will lead to premature aging".

Compared with 3 years ago, the interviews on the Internet have become increasingly fierce on the selection of pet clone.

"Calone pets can't copy its memory, and make love"

"Human surrogacy is illegal, but animal surrogacy can be used to make a profit, which is really cruel."

"What is not good for 380,000 to do?

The most comments are "no need."

I have also thought that the memory of pets cannot be copied. The surrogate dogs are pitiful, and the cost is very expensive. You can also adopt one. But at the moment of making a decision, her most urgent consideration is "unable to lose". There is no better way to retain it than cloned, and this matter is legitimate, she also spent the money she made by herself.

In fact, the two dogs of the parents' parents were adopted stray dogs, and Lao Nini also adopted. When we talked about work, we unexpectedly learned that she went to Yunnan for teaching every year. This year is the eighth year. I rarely take the initiative to mention these things with others, and feel that this seems to be deliberately looking like a good person, "but I am just an ordinary person." During the interview, she asked a somewhat absurd question: Do you say whether the public cares about ethics or money?

380,000, she spent almost all savings, including several stocks sold at low. At the beginning, she even cheated her father to say "as long as 20,000", and then her story came to the news that her father knew the truth.

"Parents think that I spend money on me. People in the previous generation will never use the money on this matter. They may be more willing to buy a car with 380,000."

Some strangers will also come to "educate" her. An unfamiliar aunt said that she also raised dogs but would never be cloned. "I asked her, what if I did it 100 yuan? She answered, then I did it. Later, I found that 95%of the people around me were not ethical, but money."

But in her opinion, there is no importance to cars, houses or other investments. "38 million clones of a dog, if it saves your spirit, is it very worth it?"

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Kono dog photography born in the laboratory: Thomas Prior

Petting aside the pet clone with human emotions as the starting point, this technology itself is the larger prospect of animal experiments.

For example, in order to study the Alzheimer's disease, animals with Alzheimer's disease are required to perform experiments. The number of experimental animals that previously suffered from this specific disease and the experimental time was very tight. Solving this problem.

The exactly the same cloning dog is experiencing pain instead of people, as a part of solving major human illnesses.

An anonymous person told one that he visited a large domestic pet clone laboratory. In a transparent room, there is a group of special autistic biogers, nearly a hundred. Putting them on a treadmill, they will always run until they are exhausted, they become the best "control variable" experimental body for self -closed.

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The first and the second clone monkey sources in the world: People's Daily

In early 2018, the Institute of neuroscience of the Chinese Academy of Sciences finally overcome difficulties and successfully cultivated the world's first body cell clone monkey "China". This is the most similar spiritual animal, which is the most useful animal model, and is further used to study human diseases.

Under this news, the enthusiastic netizens positively praised.

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Clean Cyan Hospital Photography: Thomas Prior

Famous Spiritual Activist F.Dewaal has proposed that we should not take human nature as a criterion for judging all everything. Real sympathy is not self -centered.

Nowadays, the development of animal cloning and gene editing technology seems to be running counter to it.

In 2018, Tullis Matson, the founder of a British pet clone company, took the lead in reflection -can pet cloning not only for the interests of human beings, but also for the interests of all species in the world?

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Source: documentary "Seven Worlds, One Planet"

According to the predictions of the United Nations, 1 million kinds of animals will disappear from the world in the next decades, including the black rhinos, African elephants, and Sumatra tigers that we can see ... therefore, he intends to use existing technology to cherish animals When the DNA is preserved, when they face the crisis of extinction in the future, they will bring them back in a more advanced clone.

To this end, he re -adjusted the company's research team and collected samples of rare species around the world (collect about 30 species per month, and target 1 million kinds of endangered animals DNA). In order to ensure the diversity of species, each animal has 50 samples and is stored in an ultra -low temperature liquid nitrogen box named Nature ’s Safe.

These species samples are boarding this Noah's Ark to the future.

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