Nanhua University: Chen Zhiming's study of "swallowing" cells and trying to provide new angles and solutions for disease diagnosis and treatment

It is said that interest is the best teacher, and Chen Zhiming, who is a professor and researchers, seems to have such a magic that stimulates people's interest!

▲ At present, Chen Zhiming has admitted to Hengyang Medical College of South China University in 2021.

By studying cell spot cell vomiting, help understand the occurrence of some diseases

In the explanation of Professor Chen Zhiming, studying cell swallow (that is, intracellular swallow), that is, to look at how the cell surface is eaten. "The surface of the cells not only has nutrients, but also signal transmission factor, so it not only regulates how to eat cells, but also regulates how the cells are transmitted with the external environment."

Tellastytosis is the basic process of life, which is important for creatures. "Whether it is a plant or animal, including mammals, all cells have to carry out this process." He for example, for example, the transmission of neurotic medium involved in our brain activity is also transmitted from a nerve synapper to Another synapse.

▲ Chen Zhiming hopes to help understand the occurrence of some diseases by studying cell spit vomiting.

"Once the cell spitting function is disordered, it is likely to lead to the occurrence of the disease." Chen Zhiming for example, such as some neurological diseases and cardiovascular diseases, including cancer. "We have observed that the molecular regulation mechanism of cancer cell swallowing function is different from normal cells."

Chen Zhiming said that by studying alpine vomiting, we can help us understand some diseases. "Even developing some small molecular drugs to regulate this process, let it be faster, slower, or make it more controllable, relieve it to relieve it, to relieve it to relieve it. Or reverse the disease. "

"Love fighting will win" is the spiritual support that is rooted in his bone marrow

However, Chen Zhiming can also be said to be "halfway" in this field of scientific research. He told reporters: "Before graduating from China University of Science and Technology in 2011, my major has always been the Department of Chemical Physics.

After graduating from China University of Science and Technology in 2011, Chen Zhiming came to the United States to study. Speaking of professional conversion, Chen Zhiming recalled that because he saw an article about human cell membrane systems in natural magazines, telling different membrane systems in human cells. These membrane systems are often not single and simple, but have various shapes, and their structure differences are closely related to specific functions. Chen Zhiming said: "This inspires my strong interest."

▲ Interest is the best teacher, and Chen Zhiming, as a professor, seems to have such a magic that stimulates people's interest.

At that time, the use of physical and chemical methods to study the biofilm system was a more emerging direction. "At that time, the academic community realized that using chemical and physical technical means to understand biology and explore the nature of life, it would bring new breakthroughs." Chen Zhiming thought that he had a chemical and physical knowledge background: "Although it is very challenging, And I readily accepted this cross -professional challenge! "

Since then, Chen Zhiming has joined the internationally renowned team in the field of cell membrane deformation research to study the molecular mechanism of the cellular membrane deformation in the in vitro -structure film system. J published 4 important papers.

In 2016, Dr. Chen Zhiming graduated. Subsequently, after doctoral research in the United States, the main research direction was a cell swallowing mechanism for mesh protein, and expanded its scientific training background to cell biology, structural biology, and computing biology.

▲ In Chen Zhiming's office and laboratory, the same word "love fight will win".

From domestic to abroad, from chemical physics to cell biology, from car tail gas treatment to the study of cell swallowing mechanisms in grid protein media, it means that there are multiple transformations in the middle to learn new things.

Every time the runway is converted, it is another new field, and in every field, Chen Zhiming has achieved excellent results. It is difficult for us to imagine the difficulties! However, when the reporter saw the same words in Chen Zhiming's office and laboratory, he immediately understood the power in an instant. Chen Zhiming, born in southern Fujian, the southern Fujian culture, who "loves to win" is the spiritual support that has always been rooted in his bone marrow.

"Three minutes are doomed, and seven points rely on hard work, so once you make a choice, in about a year, I will do my best to make myself stand in this field quickly."

In the future, combined with clinical swallowing and regulatory perspective provides a new perspective and plan for disease diagnosis and treatment

Born in December 1987, a member of the Communist Party of China, a professor, and a doctoral supervisor.

Published 13 academic papers in the famous international journal.

The main application of biochemistry, biophysics, and molecular cell biology is used to study the cell vesicles transportation mechanism, especially in the molecular mechanism, disease correlation and functional regulation of grid protein -mediated cells. Essence

He was invited to make a conference report at an international academic forum such as ASCB-EMBO and BPS.

Prior to the interview, Professor Chen Zhiming, who was in front of the reporter, had made the reporter marvel at his "young and promising". At present, Chen Zhiming has admitted to Hengyang Medical College of South China University in 2021.

Talking about why he returned to China, and why did you choose to come to Hunan for scientific research? Chen Zhiming admitted that when he thought to stay in 2020, he hesitated. "Because after all, I have been doing biological research in the United States after graduating from college. It may be more smooth than returning to the country than returning to China." But finally decided to return to China. In some countries, science and technology in various fields in China, he clearly realized that China Science and Technology must continue to break up and develop upward, and there are too many problems with the neck. "I'm back, maybe I am not strong enough, but what if everyone picks firewood?"

▲ Chen Zhiming guides students' experiments in the laboratory.

When choosing to come to Hunan for scientific research, Chen Zhiming also admitted that there were several places in contact at the time, but Hunan South China University felt the best. He said that the "Talent Strong School" strategy of South China University and the "Double First -class" university construction goal in 5 years "made them highly encouraged:" At present, the main school leaders are also first -line scientific research. Understanding, so I know how to support the development of the young professor team, the atmosphere is good, and it is found that it is more suitable for my concept through communication. At the same time, it is also good for the project support and platform. This helps my scientific research work. "

Therefore, in June 2021, Chen Zhiming returned to the motherland; in July, he reported to South China University and now it is just one year.

It only took less than a year, Chen Zhiming has formed a "Board Transportation Biology Laboratory" composed of young teachers, post -doctoral, doctoral students, and graduate students at Nanhua University, and set up a set of world -leading levels The working platform based on the radical microscopy imaging of the live cells and the analysis of MATLAB software, and the research platform that studies the megenrum cell mediators has filled my country ’s lack in this area.

Chen Zhiming said that at present, he can develop his heart in Hengyang, sinking down to develop, and will also encourage himself to win a new journey on the land of Hunan and Hunan with "love fighting."

At the same time, he also hopes that with the help of the work opportunities at Hengyang Medical College of Nanhua University, it has a closer connection with clinical research, so that cell swallow studies can be studied with some specific clinical diseases, including cancer, cardiovascular disease, neuroded diseases Wait. He said: "I hope to cooperate with clinical clinical, try to provide different new perspectives from the perspective of the function of swallowing function, and provide a different new perspective for the diagnosis and treatment of these diseases."

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